Stephen C. Harrison,
Ph.D.
Harvard Medical School / Howard Hughes Medical Institute
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Stephen C. Harrison is Professor
of Biological Chemistry and Molecular Pharmacology and of Pediatrics,
Harvard Medical School, and Investigator in the Howard Hughes Medical
Institute. He obtained his B.A. from Harvard in 1963 and his Ph.D. (Biophysics)
from Harvard in 1968. He has served on the Harvard faculty since 1971.
Between 1972 and 1996, he was Chair of the Board of Tutors in biochemical
Sciences, Harvard’s undergraduate program in biochemistry; he was
Chair of the Department of Biochemistry and Molecular Biology (Faculty
of Arts & Sciences) from 1988-1992. For many years, his research laboratory
was linked closely with that of the late Don C. Wiley.
Harrison has made important contributions to structural biology, most
notably by determining and analyzing the structures of viruses and viral
proteins, by crystallographic analysis of protein/DNA complexes, and by
structural studies of protein-kinase switching mechanisms. The initiator
of high-resolution virus crystallography, he has moved from his early
work on tomato bushy stunt virus (1978) to the study of more complex human
pathogens, including the capsid of human papillomavirus, the envelope
of dengue virus, and several components of HIV. He has also turned some
his research attention to even more complex assemblies, such as clathrin
coated vesicles.
Dr. Harrison is a member of the National Academy of Sciences, a fellow
of the American Academy of Arts and Sciences, a member of the American
Philosophical Society, and a foreign member of EMBO. He received the Louisa
Gross Horwitz Prize (with Don Wiley and Michael Rossmann) in 1990, the
ICN International Prize in Virology in 1998 and the Paul Ehrlich and Ludwig
Darmstaedter Prize (with Michael Rossmann) in 2001.
phone: (617) 432-5609
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