Harrison Laboratory Publications
- Allison, S.L., Tao, Y.J., O’Riordan, G., Mandl, C.W., Harrison,
S.C., Heinz, F.X. “Two distinct size classes of immature and
mature subviral particles from tick-borne encephalitis virus.” J.
Virol. 77: 11357-11366 (2003).
- Modis, Y., Ogata, S., Clements, D., and Harrison, S.C. " A ligand-binding
poicket in the dengue virus envelope glycoprotein" PNAS Early edition,
4/29/03.
- Jin, L., Sliz, P., Chen, L., Macian, F., Rao, A., Hogan, P., and Harrison,
S.C. "An asymmetric NFAT1 dimer on a pseudo-palindromic kB-like DNA
site" Nature Strutural Biology 10: 807-811 (2003).
- Espelin, C., Simons, K., Harrison, S.C., and Sorger, P. "Binding of
the Essential Saccharomyces cerevisiae Kinetochore Protein Ndc10p to
CDEII". Molecular Biology of the Cell 114: 4557-4568 (2003).
- Odegard, A.L., Chandran, K., Liemann, S., Harrison, S.C., Nibert,
M.FL. "A carboxy-proximal disulfide bond between monomers from adjacent
_1 trimers in the mammalian reovirus outer capsid: a late and reversible
step in virion morphogenesis. In press, J Virol 77 (2003).
- Harrison, S.C. "Variation on an Src-like Theme". Cell 112: 737-740
(2003).
- Sliz, P., Harrison, S.C., and Rosenbaum, G. "Damage in Protein Crystals
Depend on X-Ray Dose?" Structure 11: 13-19 (2003).
2002
- Harrison, S.C. "Don C. Wiley (1944-2001)". Molecular Cell 9: 225-227
(2002).
- Tao, Y., Farsetta, D., Nibert, M., Harrison, S.C.,"RNA Synthesis in
a Cage-Structural Studies of Reovirus Polymerase^3." Cell 111: 733-745
(2002).
- Liemann, S, Chandran, K., Baker, T.S., Nibert, M., Harrison, S.C.
"Structure of the reovirus membrane-penetration protein, _1, in a complex
with its protector protein, _3." Cell 108: 283-295 (2002).
- Dormitzer, P.R., Z.-Y. J. Sun, G. Wagner, and S.C. Harrison ."The
rhesus rotavirus VP4 sialic acid binding domain has a galectin fold
with a novel carbohydrate binding site." EMBO J 21:885-897 (2002).
- Dormitzer, P.R., Zhen-Yu J. Sun, Ola Blixt, James C. Paulson, Gerhard
Wagner, and Stephen C. Harrison. "Specificity and Affinity of Sialic
Acid Binding by the Rhesus Rotavirus VP8* Core." Virology 76, 10512-10517
(2002).
- Jin, L. and Harrison, S.C. "Structure of human calcineurin complexed
with cyclosporin A and human cyclophilin" PNAS 99: 13522-13526 (2002).
- Modis, Y., Trus, B., and Harrison S.C. "Atomic model of the papillomavirus
capsid" EMBO J. 21: 4754-4762 (2002).
2001
- Chen, X.S., Casini, G., Harrison, S.C., Garcea, R.L. "Papillomavirus
Capsid Protein Expression in Escherichia coli: Purification and Assembly
of HPV11 and HPV16 L1" J. Mol Biol. 307:173-82 (2001).
- Ferlenghi, I., Clarke, M., Ruttan, T., Allison, S., Schalich, J.,
Heinz, F., Harrison, S.C., Rey, F., and Fuller, S. "Molecular Organization
of a Recombinant Subviral Particle from Tick-Borne Encephalitis Virus",
Molecular Cell 7: 593-602, (2001).
- Lin, C.H., Hare, B.J., Wagner, G., Harrison, S.C., Maniatis, T., Fraenkel,
E. "A Small domain of CBP/p300 Binds Diverse Proteins: Solution Structure
and Functional Studies" Molecular Cell 8: 581-590 (2001).
- Harrison, S.C. "Principles of Virus Structure" in Fields Virology,
Fourth Edition, 53-85. (D.M. Knipe, P.M. Howley, et al. Lippincott Williams
& Wilkins Publishers, Philadelphia, 2001).
- Olland, A.M., Jan¹-Valbuena, J., Schiff, L.A., Nibert, M.L., Harrison,
S.C. "Structure of the Reovirus Outer Capsid and dsRNA Binding Protein
_3at 1.8 Å Resolution" EMBO J. 20: 979-989, (2001).
2000
- ter Haar, E., Harrison, S.C., Kirchhausen. T.
"Peptide-in-groove interactions link target proteins to the β-propellar of clathrin" PNAS 97: 1096-1100 (2000).
- Lei, M., Lu, W., Meng, W., Parrini, M-C., Eck, M.J., Mayer, B.J.,
Harrison, S.C. "Structure of PAK1 in an Autoinhibited Conformation Reveals
a Multistage Activation Switch." Cell 102: 387-397 (2000).
- Dormitzer, P.R., H.B. Greenberg, and S.C. Harrison . 2001. Proteolysis
of monomeric recombinant rotavirus VP4 yields an oligomeric VP5* core.
J. Virol. 75, 7339-7350.
- Luongo, C.L., Reinisch, K.M., Harrison, S.C., Nibert, M.L. "Identification
of the Guanylyltransferase Region and Active Site in Reovirus mRNA Capping
Protein _2. J. Biol. Chem. 275: 2804-2810 (2000).
- Chen, X.S., Garcea, R., Goldberg, I., Harrison, S.C. "Structure of
small virus-like particles assembled from the L1 protein of human papillomavirus
16." Molecular Cell 5: 557-567 (2000).
- Reinisch, K.M., Nibert, M., Harrison, S.C. "The Reovirus Core: Structure
of a complex molecular machine." Nature 404: 960-967 (2000).
- Chen, L., Rao., A., Harrison, S.C. "Signal Integration by Transcription-factor
Assemblies: Interactions of NF-AT1 and AP-1 on the IL-2 Promoter" Cold
Spring Harbor Symposium on Quant. Biol, Vol. LXIV: 527-531. (2000).
- Huang, H. Harrison, S.C. and Verdine, G.L. "Trapping of a catalytic
HIV reverse transcriptase-template:primer complex through a disulfide
bond." Chemistry & Biology 7: 355-364 (2000).
- Dormitzer, P.R., Greenberg, H.B., Harrison, S.C. "Purified Recombinant
Rotavirus VP7 Forms Soluble Calcium-Dependent Trimers" Virology 277:
420-428 (2000).
- Zhou, G., Ferrer, M., Chopra, R., Kapoor, T.M., Strassmaier, T., Weissenhorn,
W., Skehel, J.J., Oprian, D., Schreiber S.L., Harrison, S.C., Wiley,
D.C. "The Structure of an HIV-1 Specific Cell Entry Inhibitor in Complex
with the HIV-1 gp41 Trimeric Core" Bioorganic & Medicinal Chemistry,
8 : 2219-2227 (2000).
- Chen, B., Zhou, G, Kim, M, Chishti, Y, Hussey, R.E., Ely, B, Skehel,
J.J., Reinherz, E.L., Harrison, S.C., Wiley, D.C. Expression, purification,
and characterization of gp160, the soluble, trimeric, ectodomain of
the SIV envelope glycoprotein, gp-160. J. Biol. Chem. 275: 34946-34953
(2000).
1999
- Weissenhorn, W., Dessen, A., Calder, L. J., Harrison, S. C., Skehel,
J. J. and Wiley, D. C. "Structural basis for membrane fusion by enveloped
viruses." Molecular Membrane Biology 16 (1) 3-9, 1999.
- Xu, W., Doshi, A., Lei, M., Eck, M.J., Harrison, S.C. "Crystal structures
of c-Src reveal new features of its auto-inhibitory mechanism." Molecular
Cell, 3, 629-638, (1999).
- Ferrer, M. and Harrison, S.C. "Peptide Ligands to Human Immunodeficiency
Virus Type-1 gp120 Identified from Phage Display Libraries" J. Virol.
73: 5795-5802 (1999).
- Lawrence, C.M., Ray, S., Babyonyshev,M., Gallusser, R. Harrison, S.C.
"Structure of the Ectodomain of Human Transferrin Receptor" Science,
286: 779-782 (1999).
- Ferrer, M., Kapoor, T., Strassmaier, T., Weissenhorn, W., Skehel,
J.J., Oprian, D., Schreiber, S., Wiley, D.C., Harrison, S.C. "Selection
of gp41-Mediated HIV-1 Cell Entry Inhibitors From Biased Combinatorial
Libraries of Non-Natural Binding Elements" Nature Structural Biology
6: 953- 960 (1999).
- Musacchio, A., Smith, C.J., Roseman, A.M., Harrison, S.C., Kirchhausen,
T., Pearse, B.M.F. "Functional Organization of Clathrin Coats: Combining
Cryo-Electron Microscopy and X-ray Crystallography. Molecular Cell 3:
761-770 (1999).
- Bauer, P.H., Cui, C., Stehle, T., Harrison, S.C., DeCaprio, J.A.,
Benjamin, T.L. "Discrimination between Sialic Acid-Containing Receptors
and Pseudoreceptors Regulates Polyomavirus Spread in the Mouse" J. Virol
73: 5826-5832 (1999).
1998
- Berger, J.M., Fass, D., Wang, J.C., Harrison, S.C. Structural similarities
between topoisomerases that cleave on or both DNA strands." PNAS 95:
7876-7881 (1998).
- Chen, L., Glover, J.N.M. Patrick G. Hogan, P.G., Rao, A., Harrison,
S.C. "Structure of the DNA Binding Domains from NFAT, Fos and Jun Bound
Specifically to DNA" Nature , 392, 42-48 (1998).
- Chen, X., Stehle, T. and Harrison, S.C. "Crystal structure of a C-terminal
fragment of polyomavirus internal protein VP2 and its interaction with
VP1" EMBO J. 17: 3233-3240 (1998).
3
- Nolte, R.T., Conlin, R.M., Harrison, S.C., Brown, R.S. "Differing
roles for zinc fingers in DNA recognition: Structure of a six-finger
TFIIIA complex" PNAS 95, 2938-2931 (1998).
- Huse, M., Eck, M.J., Harrison, S.C. "A Zn2+ ion links the cytoplasmic
tail of CD4 and the N-terminal region of p56lck." J. Biol. Chem. 273,
18729-18733 (1998).
- TerHaar, E., Musacchio, A., Harrison, S.C., Kirchhausen, T. "Atomic
Structure of Clathrin: A _-Propeller Terminal Domain Joins an _-Zig-Zag
Linker" Cell 95, 563-573 (1998)
- Huang, H., Chopra, R., Verdine, G.L. and Harrison, S.C. "Structure
of a Covalently-Trapped Catalytic Complex of HIV-1 Reverse Transcriptase:
Implications for Nucleoside Analog Drug Resistance." Science, 282, 1669-1675
(1998).
- Jacobs, M.D. and Harrison, S.C. "Structure of an NF_B/I_B_ Complex"
Cell 95, 749-758 (1998).
1997
- Xu, W., Harrison, S.C. & Eck, M.J. "Three-dimensional structure of
human c-Src" Nature 385, 595-602 (1997).
- Casasnovas, J.M., Springer, T.A.,Liu, J.H., Harrison, S.C. & Wang,
J.H. "The Crystal Structure of ICAM-2 Reveals a Distinctive Integrin
Recognition Surface" Nature 387, 312-315 (1997).
- Stehle, T. & Harrison, S.C. "High-resolution structure of a polyomavirus
VP1-oligosaccharide complex: implications for assembly and receptor
binding" EMBO J. 16, 5139-5148, 1997.
- Weissenhorn, W., Dessen, A., Harrison, S.C., Skehel, J.J., Wiley,
D.C. "Atomic Structure of an Ectodomain from HIV-1 gp 41" Nature 387,
426 - 430, 1997.
- Ferrer, M., Godbout, K.L., Sullivan, B.J., Austen, D.A., Sanderson,
C.T., Kelley, K.C., Osburne, M.S., Harrison, S.C., van Schravendijk,
M "Construction and characterization of a radio-iodinatable mutant of
recombinant human CD4" J. Immunol. Methods 210, 215-225 (1997).
1996
- Harrison, S.C. "Peptide-Surface Association: The Case of PDZ and PTB
Domains" Cell 86, 341-343 (1996).
- Musacchio, A., Cantley, L.C. & Harrison, S. C. "Crystal Structure
of the breakpoint cluster region-homology domain from phosphoinositide
3-kinase p85 a subunit ." PNAS 93, 14373-78 (1996).
- Harrison, S.C., Skehel, J.J. & Wiley, D.C. "Virus Structure" in Fields
Virology, Third Edition, 59-99. (B.N. Fields, D.M. Knipe, P.M.Howley,
et al. Lippincott-Raven Publishers, Philadelphia, 1996).
- M™ller, C.W., Rey, F.A. & Harrison "Comparison of two different DNA-binding
modes of the NF-kB p50 homodimer." Nature Structural Biology 3, 224-227
(1996).
- Berger, J., Gamblin, S.J., Harrison, S.C., & Wang, J.C. "Structure
at 2.7 Å resolution of a 92K yeast DNA topoisomerase II fragment." Nature,
379, 225-232. (1996).
- Yan, Y., Stehle, T., Liddington, R.C., Zhao, H. & Harrison, S.C. "Structure
Determination of Simian Virus 40 and Murine Polyomavirus By a Combination
of 30-fold and 5-fold Electron-density Avaraging." Structure 4, 157-164
(1996).
- Stehle, T., Gamblin, S.J., Yan, Y. & Harrison, S.C. "The Structure
of Simian Virus 40 Refined at 3.1 Å Resolution." Structure 4, 165-182
(1996).
- Stehle, T., & Harrison, S.C. "Crystal Structures of Murine Polyomavirus
in Complex with Straight-chain and Branched-chain Sialyloligosaccharide
Receptor Fragments." Structure 4, 183-194 (1996).
- Roca, J., Berger, J.M., Harrison, S.C. & Wang, J.C. "DNA Transport
by Type II DNA Topoisomerase: Direct Evidence for a Two-Gate Mechanism."
PNAS, 93, 4057-4062. 1996.
- Eck, M.J., Pluskey, S., Tr™b, T., Harrison, S.C., & Shoelson, S.E.
"SpatialConstraints on the Recognition of Phosphoproteins by the tandem
SH2 Domains of the Phosphatase SH-PTP2" Nature 379, 277-280 (1996).
- Nolte, R.T., Eck, M.J., Schlessinger, J., Shoelson, S.E. & Harrison,
S.C. "Crystal Structure of the PI 3 -Kinase P85 Amino-Terminal SH2 Domain
and its Phosphopeptide Complexes" Nature Structural Biology, 3, pp.
364-374 (1996).
- Weissenhorn, W., Eck, M.J., Harrison, S.C., & Wiley, D.C. "Phosphorylated
T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex
in vitro" Euro. J. Biochem. 238: 440-445 (1996).
- Fass, D., Harrison, S.C. & Kim, P.S. "Retrovirus envelope domain at
1.7 Å resolution" Nature Structural Biology 3, 465-469 (1996).
1995
- Glover, J.N.M., & Harrison, S.C. "The Crystal Structure of the Heterodimeric
bZIP Transcription Factor c-Fos:c-Jun Bound to DNA." Nature, 373, 257-261.
1995
- Rodgers, D.W., Gamblin, S.G. Harris, B.A., Ray, S., Culp, J.S., Hellmig,
B., Woolf, D.J., Debouck, C. & Harrison, S.C. "The structure of unliganded
reverse transcriptase from the human immunodeficiency virus type 1."
PNAS, 92, 1222-1226 (1995).
- M™ller, C.W., Rey, F.A., Sodeoka,M., Verdine, G.L., & Harrison, S.C.
"Structure of the NF-kB p50 homodimer bound to DNA. Nature, 373, 311-317
1995.
- Harrison, S.C. "Virus structures and conformational rearrangements"
Current Opinion in Structural Biology 5, 157-164 (1995).
- Rey, F.A., Heinz, F. X., Mandl, C., Kunz, C. & Harrison, Stephen C.
"The envelope glycoprotein from tick-borne encephalitis virus at 2 Å
resolution." Nature, 75, 291-298(1995).
- M™ller, C.W. & Harrison, S.C. "The structure of the NF-kB p50:DNA
complex: A starting point for analyzing the Rel family." FEBS, 369,
113-117(1995).
- Bauer, P.H., Bronson, R.T., Fung, S.C., Freund, R., Stehle, T., Harrison,
S.C. & Benjamin, T.L. "Genetic and Structural Analysis of a Virulence
Determinant in Polyoma VP1" J. Virol.69, 7925-7931 (1995).
- Glover, J.N.M., Chen, L., Verdine, G.L., & Harrison, S.C. "A Structural
Analysis of the bZIP Family of Transcriptin Factors: Dimerization, DNA
Binding and Interactions with Other Transcription Factors" in Biol.
Struct. and Dynamics. Proceedings of the Ninth Conversation, SUNY Albany,
NY 1995 (Eds. Ramaswany H. Sarma and Mukti H. Sarma, Adenine Press 1996).
1994
- Barouch, D.H. & Harrison, S.C. "The Interaction Between the Major
and Minor Coat Proteins of Polyomavirus" J. Virol., 68, 3982-3989 (1994).
- Harrison, S.C. "CD4 - the receptor for HIV." in Cellular Receptors
for Animal Viruses (editor, E. Wimmer), Chapter 3. (Cold Spring Harbor
Laboratory Press, New York, 1994).
- Eck, M.J., Atwell, S.K., Shoelson, S.E. & Harrison, S.C. "Structure
of the regulatory domains of the Src-family tyrosine kinase p56lck."
Nature, 368, 764-769 (1994).
- Ellenberger, T., Fass, D., Arnaud, M. & Harrison, S.C. "Crystal Structure
of Transcription Factor E47: E-box Recognition by a Basic Region Helix-loop-helix
Dimer" Genes & Development, 8, 970-980(1994).
- Stehle, T., Yan, Y., Benjamin, T.L. & Harrison, S.C. "Structure of
murine polyomavirus complexed with an oligosaccharide receptor fragment."
Nature, 369, 160-163 (1994).
- Marmorstein, R. & Harrison, S.C. "Crystal Structure of a PPR1-DNA
Complex: DNA Recognition by Proteins Containing a Zn2Cys6 Binuclear
Cluster." Genes & Development, 8, 2504-2512. (1994)
- Rodgers, D.W. "Cryocrystallography." Structure, 2, 1135-1140 (1994).
1993
- Shimon, L.J.W. & Harrison, S.C. "The Phage 434 OR2/R1-69 Complex at
2.5 Å Resolution" J. Mol. Biol., 232, 826-838 (1993).
- Garrett, T.P.J., Wang, J., Yan, Y., Liu, J., Harrison, S.C. "Refinement
and analysis of the structure of the first two domains of human CD4"
J.Mol. Biol 234, 763-778 (1993).
- Eck, M.J. Shoelson, S.E., Harrison, S.C. "Recognition of a high affinity
phosphotyrosyl peptide by the Src homology domain of p56lck" Nature,
362, 87-91 (1993).
- Liddington R.C. and Harrison, S.C. "Structure of simian virus 40."
Structure 0, xxii-xxiii (1993).
- Moebius, U., Pallai, P., Harrison, S.C. Reinherz, E.L. "Delineation
of an extended surface contact area on human CD4 involved in class II
MHC binding" PNAS, 90, 8259-8263 (1993).
- Harrison, S.C. "Structure and Interactions of an Ig-superfamily Adhesion
Molecule" Accounts in Chemical Research, 26, 449-453(1993).
- Yan, Y., Winograd, E., Viel. A., Cronin, T., Harrison, S.C. and Branton,
D. "Atomic Structure of the Repetitive Segments of Spectrin" Science,
262, 2027-2030 (1993).
- Rodgers, D.W. & Harrison, S.C. "The complex between phage 434 repressor
DNA binding domain and operator site OR3: structural differences between
consensus and non-consensus half-sites." Structure, 1, 227-240 (1993).
1992
- Baleja, J.D., Marmorstein, R., Harrison, S.C., Wagner, G. "Solution
Structure of the DNA-binding Domain of Cd2-GAL4 from Saccharomyces cerevisiae"
Nature (1992)356, 450-453.
- Marmorstein, R., Carey,M., Ptashne, M., Harrison, S.C. "DNA Recognition
by GAL4: structure of a protein/DNA complex" Nature 356: 408-414 (1992).
- Harrison, S.C., Strong, R.K., Schlesinger, S., Schlesinger, M.J. "Crystallization
of Sindbis Virus and its Nucleocapsid"J.Mol. Biol 226: 277-280 (1992).
- Harrison, S.C. "Viruses" Current Opinion in Structural Biology 2:
293-299. (1992)
- Moebius, U., Clayton, L., Abraham, S., Harrison S.C., Reinherz, E.L.
"The HIV gp120 binding site on CD4: Delineation by quantitative equilibrium
and kinetic binding studies of mutants in conjunction with a high resolution
CD4 atomic structure " J. Exp. Med. 176, 507-517 (1992).
- Moebius, U., Clayton, L.K., Abraham, S., Diener, A., Yunis, J.J.,
Harrison, S.C. & Reinherz, E.L. "The HIV-gp120 Binding C'C" Ridge of
CD4 Domain 1 is Also Involved in Interaction with Class II MHC Molecules"
PNAS 89, 12008-12012. (1992).
- Harrison, S.C. "Molecular characteristics of the regulatory switch
in phages 434 and lambda" in Transcriptional Regulation (ed. by K. Yamamoto
& S. McKnight) Ch. 17, 449-473 (Cold Spring Harbor Laboratory Press,
New York 1992).
- Harrison, S.C., Wang, J., Yan, Y., Garrett, T., Liu, J., Moebius,
U., Reinherz, E.L. "Structure and Interactions of CD4" Cold Spring Harbor
Laboratory Symposia on Quantitative Biology 57, 541-548 (1992).
- Harrison, S.C., Wang, J., Yan, Y., Garrett, T., Liu, J., Moebius,
U., Reinherz, E.L. "Structure and Interactions of CD4" Proceedings of
Novo Nordisk Foundation Symposium No. 6 'Leukocyte Adhesion' Basic and
Clinical Aspects (Elsevier Publishers, Holland, C.G. Gahmberg, T. Mandrup-Poulsen,
L. Wogensen Bach, B. Hðkfelt, eds.1992) pp. 255-269.
- Ellenberger, T.E., Brandl, C.J., Struhl, K., Harrison, S.C. "The GCN4
Basic-Region-Leucine Zipper Binds DNA as a Dimer of Uninterrupted a-helices:
Crystal Structure of the Protein-DNA Complex" Cell 71, 1223-1237 (1992).
1991
- Harrison, S.C. "Viruses" in Current Opinion in Structural Biology
Vol. 1/2 1, 288-295 (1991).
- Harrison, S.C. "A structural taxonomy of DNA-binding domains" Nature
(1991) 353, 715-719.
- Liddington, R.C., Yan, Y, Moulai, J., Sahli, R., Benjamin, T.L., Harrison,
S.C. "Structure of Simian Virus 40 at 3.8 Å resolution" Nature 354,
278-284 (1991).
- Mondragon, A. and Harrison, S.C. "The Phage 434 Cro/OR1 Complex at
2.5 Å Resolution" J. Mol. Biol. 219, 321-334 (1991).
- Borhani, D. and Harrison, S.C. "Crystallization and X-ray Diffraction
Studies of a Soluble Form of Human Transferrin Receptor" J. Mol. Biol.
218, 685-689 (1991).
- Harrison, S.C. "What Do Viruses Look Like?" The Harvey Lectures, Series
85, 127-152. Wiley-Liss, Inc (1991).
1990
- S.C. Harrison . "Principles of Virus Structure" in Fundamental Virology,
2nd Ed. pp. 37-61. (Raven Press, NY; Fields and Knipe, ed. 1990).
- C.O. Pabo, A.K.Aggarwal, S.R. Jordan, L.J. Beamer, U.R. Obeysekare,
S.C. Harrison "Conserved Residues Make Similar Contacts in Two Repressor-Operator
Complexes." Science 247: 1210-1213 (1990).
- S.C. Harrison and A.K. Aggarwal. "DNA Recognition by Proteins with
the helix-turn-helix motif." in Annual Rev. of Biochem.,59: 933-69 (1990).
- N. Wei, L. A. Heaton, T.J. Morris and S.C. Harrison "Structure and
Assembly of Turnip Crinkle Virus V. Identification of Coat Protein Binding
Sites on RNA" J. Mol. Biol. 214, 85-95 (1990).
- R.K. Strong and S.C. Harrison ."Proteolytic Dissection of Sindbis
Virus Core Protein" J. Virology 64, 3992-3994 (1990).
- J.W. Campbell, I.J. Clifton, T.J. Greenhough, J. Hajdu, S.C. Harrison
, R.C. Liddington, A.K. Shrive. "Calcium Binding Sites in Tomato Bushy
Stunt Virus Visualized by Laura Crystallography" J. Mol. Biol. 214,
627-632.(1990).
- Coombs, K.M., Fields, B.N. and Harrison, S.C. "Crystallization of
the reovirus type 3 Dearing core: Crystal packing is determined by the
l protein." J. Mol. Biol. 215, 1-5 (1990).
- Weiss, M.A., Ellenberger, T., Wobbe, C.R., Lee, J.P., Harrison, S.C.,
Struhl, K. Folding transition in the DNA-binding domain of GCN4 on specific
binding to DNA" Nature 347, 575-578 (1990).
- Harrison, S.C. "Common features in the structures of some icosahedral
viruses: a partly historical overview" in Seminars in Virology,1, W.B.
Saunders Company pp 387-403 (1990).
- Wang, J., Garrett, T., Yan, Y., Liu, J., Rodgers, D., Garlick, R.L.,
Tarr, G.E., Husain, Y., Reinherz, E.L., Harrison, S.C. "Atomic structure
of a fragment of human CD4 containing two immunoglobulin-like domains"
Nature 348 411-418 (1990).
- Heinz, F.X., Mandl, C.W., Holzmann, H., Kunz, C., Harris, B.A., Rey,
F., Harrison, S.C. "The Flavivirus Envelope Protein E: Isolation of
a Soluble Dimeric Form from Tick-Borne Encephalitis Virus and Its Crystallization"
J. Virol. 65, 5579-5583 (1990).
1989
- A. Mondragon, C. Wolberger and S.C. Harrison . "Structure of Phage
434 Cro Protein at 2.35 Å Resolution." J. Mol. Biol., 205, 179-188 (1989).
- S.C. Harrison . "Finding the Receptors." Nature 338, 205-206 (1989).
- A. Mondragon, S. Subbiah, S.C. Almo, M. Drottar and S.C. Harrison
"Structure of the Amino Terminal Domain of Phage 434 Repressor at 2.0
Å Resolution." J. Mol. Biol., 205 189-200 (1989).
- A.P. Turkewitz and S.C. Harrison "Concentration of Transferrin Receptor
in Human PlacentalCoated Vesicles." J. Cell. Biol., 108: 2127-2135 (1989).
- S. Subbiah and S.C. Harrison ."A simulated annealing approach to the
search problem of protein crystallography." Acta Cryst. A45, 337-342
(1989).
- S. Subbiah and S.C. Harrison ."A Method for Multiple Sequence Alignment
with Gaps" J. Mol. Biol. 206, 539-548 (1989).
- S.C. Harrison . "Common Features in the Design of Small RNA Viruses."
in Concepts in Viral Pathogenesis III pp. 3-19 (Springer-Verlag New
York, Inc.,1989).
1988
- S.C. Harrison , J.E. Anderson, G.B. Koudelka, A. Mondragon, S. Subbiah,
R.P. Wharton, C.Wolberger and M. Ptashne. "Recognition of DNA Sequences
by the Repressor of Bacteriophage 434". Biophysical Chemistry 29, 31-37
(1988).
- S.C. Harrison , J.E. Anderson, Y-C. Dong, M. Drottar, G.B. Koudelka,
A. Mondragon, S. Subbiah,R.P. Wharton, C. Wolberger and M. Ptashne.
"Recognition of DNA Sequences by the Repressor and Cro Proteins of Bacteriophage
434." Proceedings of the Symposium Louis Pasteur, 1987. Bulletin Institute
Pasteur 86, 55-64 (1988).
- A.P. Turkewitz, J.F. Amatruda, D. Borhani, S.C. Harrison , and A.L.
Schwartz. "A High Yield Purification of the Human Transferrin Receptor
and Properties of Its Major Extracellular Fragment." J. Biol. Chem.
263, No. 17, pp. 8318-8325. (1988).
- G.B. Koudelka, P. Harbury, S.C. Harrison , M. Ptashne. "DNA Twisting
and the Affinity of Bacteriophage 434 Operator for Bacteriophage 434
Repressor." PNAS.USA 85: 4633-4637 (1988).
- C. Wolberger, Y. Dong, M. Ptashne and S.C. Harrison . "Structure of
a Phage 434 Cro/DNA Complex." Nature 335, 789-795 (1988).
- A. Aggarwal, D. Rodgers, M. Drottar, M. Ptashne, and S.C. Harrison
. "Recognition of a DNA Operator by the Repressor of Phage 434: a View
at High Resolution." Science 242, 899-907 (1988).
- A.P. Turkewitz, A.L. Schwartz and S.C. Harrison . "A pH-Dependent
Reversible Conformational Transition of the Human Transferrin Receptor
Leads to Self-Association." J. Biol. Chem., 263, 16309-16315 (1988).
1987
- J. Carrington, T. J. Morris, P. G. Stockley, and S.C. Harrison "Structure
and Assembly of Turnip Crinkle Virus, IV: Analysis of the Coat Protein
Gene and Implications of the Subunit Primary Structure." J. Mol. Biol.
194, 265-276 (1987).
- S.C. Harrison, P. K. Sorger, P.G. Stockley, J. Hogle, R. Altman, and
R.K. Strong. "Mechanism of RNA VirusAssembly and Disassembly." in Positive
Strand RNA Viruses,. Alan R. Liss, Inc., 379-395 (1987).
- J. E. Anderson, M. Ptashne, and S.C. Harrison "Structure of the Bacteriophage
434 Repressor-Operator Complex." Nature 326, 846-852 (1987).
- G. B. Koudelka, S.C. Harrison, and M. Ptashne. "Non-contacted Bases
Affect the Operator Affinities of 434 Repressor and Cro." Nature 326,
886-888 (1987).
- C. Wolberger and S.C. Harrison "Crystallization and X-ray Diffraction
Studies of a 434 Cro-DNA Complex." J. Mol. Biol. 196, 951-954 (1987).
- M. Blum, P. Metcalf, S.C. Harrison, and D. C. Wiley. "A System for
Collection and On-line Integration of X-ray Diffraction Data from a
Multiwire Area Detector." J. Appl. Cryst.20, 235-242 (1987).
- T. Kirchhausen, P. Scarmato, S.C. Harrison , J.J. Monroe, E.P. Chow,
R.J. Mattaliano, K.L. Ramachandran, J.E. Smart and J. Brosius. "Clathrin
Light Chains LCA and LCB are Similar, Polymorphic, and Share Repeated
Heptad Motifs." Science 236, 320-324(1987).
1986
- R. Durbin, R. Burns, J. Moulai, P. Metcalf, D. Freymann, J. Anderson,
S.C. Harrison, and D. C.Wiley. "Protein, DNA, and Virus Crystallography
with a Focused Imaging Proportional Counter." Science 232,1127-1132
(1986).
- S.C. Harrison "Alphavirus Structure," Chapter 2 of The Togaviridae
and Flaviviridae (S. and M. Schlesinger, eds., Plenum Publishing Corp.,
1986).
- J. M. Hogle, A. Maeda, and S.C. Harrison "Structure and Assembly of
Turnip Crinkle Virus, I:X-ray Crystallographic Structure Analysis at
3.2 Å Resolution." J. Mol. Biol. 191, 625-638 (1986).
- P. K. Sorger, P. G. Stockley, and S.C. Harrison "Structure and Assembly
of Turnip Crinkle Virus, II: Mechanism of in vitro Reassembly." J. Mol.
Biol. 191,. 639-658 (1986).
- P. G. Stockley, A. L. Kirsh, E. P. Chow, J. E. Smart, and S.C. Harrison
"Structure of TurnipCrinkle Virus, III: Identification of a Unique Coat
Protein Dimer." J. Mol. Biol. 191,721-725 (1986).
- T. Kirchhausen, S.C. Harrison, and J. Heuser. "Configuration of Clathrin
Trimers: Evidence from Electron Microscopy." J. of Ultrastructure and
Mol. Structure Research 94,199-208 (1986).
1985
- S.C. Harrison "Principles of Virus Structure" in Virology (ed. B.
N. Fields et al.; Raven Press, New York), 27-44 (1985).
- S.C. Harrison . "First comparison of two animal viruses in three
dimensions." Nature 317, 382-384, News and Views (1985).
- S.C. Harrison . "Protein Structures. Two for the price of one." Nature
313, 736-737, News and Views (1985).
- S.C. Harrison and R. Durbin. "Is There a Single Pathway for the Folding
of a Polypeptide Chain?" Proc. Natl. Acad. Sci. USA 82, 4028-4030 (1985).
- T. Kirchhausen, J.C. Wang, and S.C. Harrison . "DNA Gyrase and its
Complexes with DNA: Direct Observation by Electron Microscopy." Cell
41, 933-943 (1985).
- S.C. Harrison, F. K. Winkler, C. E. Schutt, and R. M. Durbin. "Oscillation
Method with Large Unit Cells," in Methods in Enzymology. Vol. 114, Part
A (eds. Colowick and Kaplan, Academic Press, Inc., Orlando, FLA, 1985).
- J. Anderson, M. Ptashne, and S.C. Harrison "A Phage Repressor-Operator
Complex at 7 Å Resolution." Nature 316, 596-601 (1985).
- F.D. Bushman, J. Anderson, S.C. Harrison , and M. Ptashne. "Ethylation
Interference and X-ray Crystallography Identify Similar Interactions
Between 434 Repressor and Operator." Nature 316, 651-653 (1985).
- S.C. Harrison and T. Kirchhausen. "Molecular Interactions in Receptor
Cycling and Endocytosis by Clathrin-Coated Vesicles." TIBS Centerfold,
October 1985.
1984
- J. Anderson, M. Ptashne, and S.C. Harrison "Co-crystals of the DNA-binding
Domain of Phage 434 Repressor and a Synthetic Phage 434 Operator." Proc.
Nat'l. Acad. Sci. USA 81,1307-1311 (1984).
- S.C. Harrison "Structures of Viruses" in The Microbe 1984: Part 1
Viruses (ed. B. W. J. Mahy and J. R. Pattison), Soc. Gen. Microbiol.
Symposium 36, pp. 29-73 (1984).
- P. Hopper, S.C. Harrison, and R. Sauer. "Structure of Tomato Bushy
Stunt Virus V: Protein Sequence Determination and its Structural Implications."
J. Mol. Biol. 177, 701-713 (1984).
- S C. Harrison. "Multiple Modes of Subunit Association in the Structures
of Simple Spherical Viruses." TIBS Vol. 9, No. 1, pp. 345-351 (1984).
- T. Kirchhausen, J. Wang, and S.C. Harrison "Structural Studies of
DNA Gyrase." Proceedings of the 42nd Annual Meeting of the Electron
Microscopy Society of America (1984)
- T. Kirchhausen and S.C. Harrison "Structural Domains of Clathrin Heavy
Chains." J. Cell.Biol. 99: 1725-34 (1984).
1983
- T. Kirchhausen, S.C. Harrison, P. Parham, and F. M. Brodsky. "Location
and Distribution of the Light Chains in Clathrin Trimers." Proc. Nat.
Acad. Sci. USA 80, 2481-85 (1983).
- S. C. Harrison and T. Kirchhausen. "Clathrin, Cages, and Coated Vesicles."
Cell 33, 650-652 (1983).
- S.C. Harrison " Virus Structure: High Resolution Perspectives" in
Advances in Virus Research.Vol. 28 (eds. M. Lauffer and K. Mamamorosch)
Academic Press, Inc., New York, 1983; pp. 175-240 (1983).
- A. J. Olson, G. Bricogne, and S.C. Harrison "Structure of Tomato Bushy
Stunt Virus, IV: The Virus Particle at 2.9 Å Resolution." J. Mol. Biol.
171. 61-93 (1983).
- J. Hogle, T. Kirchhausen, and S.C. Harrison "Divalent Cation Sites
in Tomato Bushy Stunt Virus: Difference Maps at 2.9 Å Resolution." J.
Mol. Biol., 171, 95-100 (1983).
- S.C. Harrison "Packaging of DNA into Bacteriophage Heads - A Model."
J. Mol. Biol. 171, 577-580 (1983).
1982
- J. S. Golden and S.C. Harrison "Proteolytic Dissection of Turnip Crinkle
Virus Subunit in Solution." Biochem. 16, 3862 (1982).
- I. K. Robinson and S.C. Harrison "Structure of the Expanded State
of Tomato Bushy StuntVirus." Nature 297, 563 (1982).
1981
- S.C. Harrison "Molecular Packing of Nucleic Acids in Spherical Viruses."
in Biological Recognition and Assembly (eds. D. S. Eisenberg, J. A.
Lake and C. F. Fox) Alan R. Liss, New York, 1980; p. 301.
- S.C. Harrison "Molecular Organization of Virus Particles: Implications
for Assembly." Prog. Clin. Biol. Res. 64, 3 (1981).
- T. Kirchhausen and S.C. Harrison "Protein Organization in Clathrin
Trimers." Cell 23, 755 (1981).
1980
- S.C. Harrison . "Virus Crystallography Comes of Age." Nature 286,
558-559, News and Views (1980).
- S.C. Harrison "Protein Interfaces and Intersubunit Bonding: The Case
of Tomato Bushy Stunt Virus." Biophys. J. 32,139-153. (1980).
- M. G. Munowitz, C. M. Dobson, R. G. Griffin, and S.C. Harrison "On
the Rigidity of RNA in Tomato Bushy Stunt Virus." J. Mol Biol. 141,
327 (1980).
1979
- F. K. Winkler, C. E. Schutt, and S.C. Harrison "The Oscillation Method
for Crystals with Very Large Unit Cells." Acta Cryst. A35, 901(1979).
1978
- S.C. Harrison "Structure of Simple Viruses: Specificity and Flexibility
in Protein Assemblies." TIBS 3, 3 (1978).
- W. C. Earnshaw, J. King, S.C. Harrison, and F. A. Eiserling. "The
Structural Organization of DNA Packaged within the Heads of T4 Wild-Type,
Isometric and Giant Bacteriophages." Cell 14, 559 (1978).
- S.C. Harrison, A. J. Olson, C. E. Schutt, F. K. Winkler, and G. Bricogne.
"Tomato Bushy Stunt Virus at 2.9 Å Resolution." Nature 276, 368 (1978).
- C. H. von Bonsdorff and S.C. Harrison "Hexagonal Glycoprotein Arrays
from Sindbis Virus Membranes" J. Virol. 28, 578 -583. (1978).
1977
- F. K. Winkler, C. E. Schutt, S.C. Harrison, and G. Bricogne. "Tomato
Bushy Stunt Virus at 5.5 ÅResolution." Nature 265, 509 (1977).
- McCarthy, M. and Harrison, S.C. "Glycosidase Susceptibility: aProbe
for the Distribution of Glycoprotein Oligosaccharides in Sindbis Virus."
J. Virol. 23. 61-73. (1977).
- W. C. Earnshaw and S.C. Harrison "DNA arrangement in Isometric Phage
Heads." Nature 268, 598 (1977).
- G. Bricogne, S.C. Harrison, F. K. Winkler, and others. Report of CECAM
Workshop on Virus Crystallography (1977).
1976
- W. Earnshaw, S. Casjens, and S.C. Harrison "X-ray Diffraction from
P22 Heads." J. Mol. Biol.104, 387 (1976).
- S.C. Harrison and R. D. Kornberg. "X-ray Diffraction from Isolated
Repeat Units of Chromatin," in Molecular Mechanisms in the Control of
Gene Expression (Academic Press, 1976).
1975
- H. von Bonsdorff and S.C. Harrison "Sindbis Virus Glycoproteins Form
a RegularIcosahedral Surface Lattice." J. Virol. 16, 141 (1975).
- C. Cohen, S.C. Harrison, and R. E. Stephens. "X-ray Diffraction from
Microtubules." J. Mol. Biol. 59, 375 (1975).
- C. Cohen, D. DeRosier, S.C. Harrison, R. E. Stephens, and J. Thomas.
"X-ray Patterns from Microtubules." Ann. New York Acad. Sci. 254, 53
(1975).
- A. Jack, S.C. Harrison, and R. A. Crowther. "Structure of Tomato Bushy
Stunt Virus, II. Comparison of Results Obtained by Electron Microscopy
and X-ray Diffraction." J. Mol. Biol. 97, 163 (1975).
- S.C. Harrison and A. Jack. "Structure of Tomato Bushy Stunt Virus,
III. Three-Dimensional X-ray Diffraction Analysis at 16 Å Resolution."
J. Mol. Biol. 97, 173 (1975).
- A. Jack and S.C. Harrison "On the Interpretation of Small-Angle X-ray
Solution Scattering from Spherical Viruses." J. Mol. Biol. 99,15 (1975).
- D. H. Ohlendorf, M. L. Collins, E. 0. Puronen, L. J. Banaszak, and
S.C. Harrison "CrystallineLipoprotein Phosphoprotein Complex in Oocytes
from Xenopus laevis: Determinationof Lattice Parameters by X-ray Crystallography
and Electron Microscopy." J. Mol.Biol. 99,153 (1975).
1974
- A. Ziegler, S.C. Harrison, and R. Leberman. "Minor Proteins in Tomato
Bushy Stunt and Turnip Crinkle Viruses." Virology 59, 509 (1974).
- S.C. Harrison, A. Jack, D. Goodenough, and B. Sefton. "Structural
Studies of Spherical Viruses." J. Supramolec. Structure 2, 486 (1974).
1973
- Y. DuPont, S.C. Harrison, and W. Hasselbach. "Molecular Organization
in the Sarcoplasmic Reticulum Membrane Studied by X-ray Diffraction."
Nature 244, 555 (1973).
- S.C. Harrison "Biological Diffraction" in Research Application of
Synchrotron Radiation. Brookhaven National Laboratory, BNL-50381(1973).
- S.C. Harrison, D. L. D. Caspar, D. Camerini-Otero, and R. M. Franklin.
"Lipid and Protein Arrangement in Bacteriophage PM2." Nature New Biol.;
229,197 (1971).
- S.C. Harrison, A. David, J. Jumblatt, and J. E. Darnell. "Lipid and
Protein Organization in Sindbis Virus." J. Mol. Biol. 60, 523-528 (1971).
- S.C. Harrison "Structure of Tomato Bushy Stunt Virus at 25 Å Resolution."
Cold Spr. Harb.Symp. Quant. Biol. XXXVI, 495 (1971).
- R. M. Franklin, S.C. Harrison, U. Petterson, L. Philipson, C. Braden,
and P. E. Werner."Structural Studies on the Adenovirus Hexon." Cold
Spr. Harb. Symp. Quant. Biol.XXXVI, 503 (1971).
1970
- K. Weber, J. Rosenbusch, and S.C. Harrison "Structure of Tomato Bushy
Stunt Virus." Virology 41, 763 (1970).
1969
S.C. Harrison "Structure of Tomato Bushy Stunt Virus. I. The Spherically Averaged Electron Density." J. Mol. Biol. 42 457 (1969).
1968
- S.C. Harrison "A Point Focusing Camera for Single-Crystal Diffraction."
J. Appl. Cryst. 1, 84 - 90. (1968).
1967
- S.C. Harrison "The Structure of Tomato Bushy Stunt Virus." Ph.D. Thesis,
Harvard University, 1967.
1966
- J. M. Diamond and S.C. Harrison "The Effect of Membrane Fixed Charges
on Diffusion Potentials and Streaming Potentials." J. Physiol. 183,
37 (1966).
1965
- S.C. Harrisonand E. R. Blout. "Reversible Conformational Changes of Myoglobin and Apomyoglobin." J. Biol. Chem. 240, 299 (1965).
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