Harrison Laboratory Publications


2014

  • Fera, D., Schmidt, A.G., Haynes, B.F., Gao, F., Liao, H-X., Kepler, T.B., Harrison, S.C. Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. PNAS 111(28): 10275-80 (2014).

2013

  • Hinshaw, S.M. and Harrison, S.C. An ImI3-ChI4 Heterodimer Links the Core Centromere to Factors Required for Accurate Chromosome Segregation. Cell Reports 5: 1-8 (2013).

  • Ivanovic, T., Choi, J.L., Whelan, S.P., van Oijen, A.M., Harrison, S.C. Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates. eLIFE 1: 1-20 (2013).

  • Klein, D.E., Choi, J.L., Harrison, S.C. Structure of a Dengue Virus Envelope. J. Virol. 87(4): 2287-2293 (2013).

  • Alam, S.M., Liao, H-X., Tomaras, G.D., Bonsignori, M., Tsao, C-Y., Hwang, K-K., Chen, H., Lloyd, K.E., Bowman, C., Sutherland, L., Jeffries, T.L., Kozonk, D.M., Stewart, S., Anasti, K., Jaeger, F.H., Parks, R., Yates, N.L., Overman, R.G., Sinangil, F., Berman, P.W., Pitisuttihum, P., Kaewkungwal, J., Nitayaphan, S., Karasavva, N., Reks-Ngarm, S., Kim, J.H., Michael, N.L., Zolla-Pasner, S., Santra, S., Letvin, N.L., Harrison, S.C., Haynes, B.F. Antigenicity and Immunogenicity of RV144 Vaccine AIDSVAX Clade E Envelope Immunogen is Enhanced by a gp120 N-Terminal Deletion. J. Virol. 87(3): 1554-1568 (2013).

  • Estrozi, L.F., Settembre, E.C., Goret, G., McClain, B., Zhang., X., Chen, J.Z., Grigorieff, N., Harrison, S.C. Location of the dsRNA-Dependent Polymerase, VP1, in Rotavirus Particles. J. Mol. Biol. 425: 124-132 (2013).

  • Schmidt, A.G., Xu, H., Khan, A.R., O'Donnell, T., Khurana, S., King, L.R., Manischewitz, J., Golding, H., Suphaphiphat, P., Carfi, A., Settembre, E.C., Dormitzer, P.D., Kepler, T.B., Zhang, R., Moody, M.A., Haynes. B.F., Liao, H-X., Shaw, D.E., Harrison, S.C. Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. PNAS 110 (1): 264-269 (2013).

2012

  • Campbell, M.G., Cheng, A., Brilot, A.F., Moeller, A., Lyumkis, D., Veesler, D., Pan, J., Harrison, S.C., Potter, C.S., Carragher, B., Grigorieff, N. Movies of Ice-Embedded Particles Enhance Resolution in Electron Cryo-Microscopy. Structure 20: 1823-1828 (2012).

  • Corbett, K.D. and Harrison, S.C. Molecular Architecture of the Yeast Monopolin Complex. Cell Reports 1: 583-589 (2012).

  • Haynes, B.F., Kelsoe, G., Harrison, S.C., Kepler, T.B. B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study. Nature Biotechnology 10 (5): 423 (2012).

  • Schmidt, A. G., Lee, K., Yang, P. L., Harrison, S. C. Small-molecule inhibitors of dengue-virus entry. PLoS Pathogens 8(4): 1-10 (2012).

  • Ivanovic, T., Rozendaal, R., Floyd, D. L., Popovic, M., van Oijen, A. M., Harrison, S. C. Kinetics of proton transport into influenza virions by the viral M2 channel. PLoS One 7(3): 1-9 (2012).

  • Schmitzberger, F., Harrison, S. C. RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure.. EMBO Reports 13(3): 216-222 (2012).

  • Cho, U.-S., Harrison, S. C. Ndc10 is a platform for inner kinetochore assembly in budding yeast. Nature Structure & Molecular Biology 19(1): 48-56 (2012).

2011

  • Cho, U.S., Corbett, K.D., Al-Bassam, J., Bellizzi, J.J. 3rd, De Wulf, P., Espelin, C.W., Miranda, J.J., Simons, K., Wei, R.R., Sorger, P.K., Harrison, S.C. Molecular structures and interactions in the yeast kinetochore. Cold Spring Harbor Symposium on Quantitative Biology 75: 395-401 (2011).

  • Aoki, S.T., Trask, S.D., Coulson, B.S., Greenberg, H.B., Dormitzer, P.R., Harrison, S.C. Cross-linking of rotavirus outer capsid protein VP7 by antibodies or disulfides inhibits viral entry. Journal of Virology 85(20): 10509-10517 (2011).

  • Berardi, M. J., Shih, W. M., Harrison, S. C., Chou, J. J. Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching. Nature 476: 109-114 (2011).

  • Cho, U.-S., Harrison, S.C. Recognition of the centromere-specific histone Cse4 by the chaperone Scm3. PNAS 108(23): 9367-9371 (2011).

  • Whittle, J.R.R., Zhang, R., Khurana, S., King, L.R., Manischewitz, J., Golding, H., Dormitzer, P.D., Haynes, B.F., Walter, E.B., Moody, M.A., Kepler, T.B., Liao, H-X., Harrison, S.C. Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin. PNAS 108(34): 14216-21 (2011).

  • Böcking, T., Aguet, F., Harrison, S.C., Kirchhausen, T. Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating. Nature Structural & Molecular Biology 18(3): 295-301 (2011).

  • Grigorieff, N., Harrison, S.C. Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy. Current Opinion in Structural Biology 21: 265-273 (2011).

  • Settembre, E.C., Chen J.Z., Dormitzer, P.D., Grigorieff, N., Harrison S.C. Atomic model of an infectious rotavirus particle. EMBO Journal 30(2): 408-416 (2011).

2010

  • Floyd, D.L., Harrison, S.C., van Oijen, A.M. Analysis of Kinetic Intermediates in Single-Particle Dwell-Time Distributions. Biophysical Journal 99: 360-366 (2010).

  • Schmidt, A.G., Yang, P.L., Harrison, S.C. Peptide Inhibitors of Flavivirus Entry Derived from the E Protein Stem. Journal of Virology 84(24): 12549-54 (2010).

  • Guan, R., Dai, H., Harrison, S.C., Kirchhausen, T. Structure of the PTEN-like Region of Auxilin, a Detector of Clathrin-Coated Vesicle Budding. Structure 18: 1191-1198 (2010).

  • Corbett, K.D., Yip, C.K., Ee, L., Walz, T., Amon, A., Harrison, S.C. The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell 142: 556-567 (2010).

  • Al-Bassam, J., Kim, H., Brouhard, G., van Oijen, A., Harrison, S.C., Chang, F. CLASP Promotes Microtubule Rescue by Recruiting Tubulin Dimers to the Microtubule. Developmental Cell 19: 245-258 (2010).

  • Kim, I.S., Trask, S.T., Babyonyshev, M., Dormitzer, P.R., Harrison, S.C. Effect of Mutations in VP5* Hydrophobic Loops on Rotavirus Cell Entry. J. Virol. 84(12): 6200-6207 (2010).

  • Schmidt, A.G., Yang, P.L., Harrison, S.C. Peptide Inhibitors of Dengue-Virus Entry Target a Late-Stage Fusion Intermediate. PLoS Pathog 6(4): e1000851 (2010).

  • Wolf, M., Garcea, R.L., Grigorieff, N., Harrison, S.C. Subunit interactions in bovine papillomavirus. PNAS 107 (14): 6298-6303 (2010).

  • Abraham, J., Corbett, K.D., Farzan, M., Choe, H., Harrison, S.C., Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses. Nature Structural & Molecular Biology 17: 438-444 (2010).

  • McClain, B., Settembre, E., Temple, B.R.S., Bellamy, A.R., Harrison, S.C. X-ray Crystal Structure of the Rotavirus Inner Capsid Particle at 3.8 Å Resolution . Journal of Molecular Biology 397: 587-599 (2010).

  • Trask, S.D., Kim, I.S., Harrison, S.C., Dormitzer, P.D. A Rotavirus Spike Protein Conformational Intermediate Binds Lipid Bilayers. Journal of Virology 84 (4): 1764-1770 (2010).

2009

  • Yoder, J.D., Trask, S.D., Vo, P.T., Binka, M., Feng, N., Harrison, S.C., Greenberg, H.B., Dormitzer, P.D. VP5* Rearranges when Rotavirus Uncoats. Journal of Virology 83(21): 11372-11377 (2009).

  • Xing, Yi., Böcking, T., Wolf, M., Grigorieff, N., Kirchhausen, T., Harrison, S.C, Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly. The EMBO Journal 29 (3): 655 -665 (2009).

  • Alam, S. M., Morelli, M., Dennison, S.M., Liao, H-X., Zhang, R., Xia, S-M., Rits-Volloch, S., Sun, L., Harrison, S.C., Haynes, B.F., Chen, B. Role of HIV membrane in neutralization by two broadly neutralizing antibodies. PNAS 106(47): (2009).

  • Zhang, L., Agosto, M.A., Ivanovic, T., King, D.S., Nibert, M.L., Harrison, S.C. Requirements for the Formation of Membrane Pores by the Reovirus Myristoylated μ1N Peptide. J. Virol. 83 (14): 7004-7014 (2009).

  • Chen, J.Z., Settembre, E.C., Aoki, S.T., Zhang, X., Bellamy, A.R., Dormitzer, P.D., Harrison, S.C., Grigorieff, N. Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM. PNAS 106(26): 10644-10648 (2009).

  • Aoki, S.T., Settembre, E.C., Trask, S.D., Greenberg, H.B., Harrison, S.C., Dormitzer, P.R. Structure of Rotavirus Outer-Layer Protein VP7 Bound with a Neutralizing Fab. Science 324: 1444-1447 (2009).

2008

  • Lu, X., McDonald, S.M., Tortorici, M.A., Tao, Y.J., Vasquez-Del Carpio, R., Nibert, M.L., Patton, J.T., Harrison, S.C. Mechanism for Coordinated RNA Packaging and Genome Replication by Rotavirus Polymerase VP1. Structure 16: 1678-1688 (2008).

  • Cohen, R.L., Espelin, C.W., De Wulf, P., Sorger, P.K., Harrison, S.C., Simons, K.T. Structural and Functional Dissection of Mif2, a Conserved DNA-binding Kinetochore Protein. Mol. Biol. of the Cell 19: 4480-4491 (2008).

  • Floyd, Daniel L., Ragains, Justin R., Skehel, John J., Harrison, Stephen C., van Oijen, Antoine M. Single-particle kinetics of influenza virus membrane fusion. PNAS 105(40): 15382-15387 (2008).

  • Harrison, S.C. Viral membrane Fusion. Nature Structural & Molecular Biology 15: 690-698 (2008).

  • Ivanovic, T., Agosto, M., Zhang, L., Chandran, K., Harrison, S.C., Nibert, M.L. Peptides released from reovirus outer capsid form membrane pores that recruit virus particles. The EMBO Journal 27 (8): 1289-1298 (2008).

  • Zhang, X., Settembre, E., Xu, C., Dormitzer, P.D., Bellamy, R., Harrison, S.C., Grigorieff, N. Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction. PNAS 105 (6): 1867-1872 (2008).

  • Brouhard, G.J., Stear, J.H., Noetzel, T.L., Al-Bassam, J., Kinoshita, K., Harrison, S.C., Howard, J., Hyman, A.A. XMAP215 Is a Processive Microtubule Polymerase. Cell 132: 79-88 (2008).

2007

  • Bellizzi, J.J.III, Sorger, P.K., Harrison, S.C. Crystal Structure of the Yeast Inner Kinetochore Subunit Cep3p. Structure 15: 1422-1430 (2007).

  • Miranda, JJ, King, D.S., Harrison, S.C. Protein Arms in the Kinetochore-Microtubule Interface of the Yeast DASH Complex. Molecular Biology of the Cell 18: 2503-2510 (2007).

  • Panne, D., Maniatis, T., Harrison, S.C. An Atomic Model of the Interferon-β Enhanceosome. Cell 129: 1111-1123 (2007).

  • Li, H., Zhang, L., Rao, A., Harrison, S.C., Hogan, P.G. Structure of Calcineurin in Complex with PVIVIT Peptide: Portrait of a Low-affinity Signalling Interaction. J. Mol. Biol. 369: 1296-1306 (2007).

  • Cheng, Y., Boll, W., Kirchhausen, T., Harrison, S.C., Walz, T. Cryo-electron Tomography of Clathrin-coated Vesicles: Structural Implications for Coat Assembly. J. Mol. Biol. 365: 892-899 (2007).

  • Al-Bassam, J., Larsen, N.A., Hyman, A.A., Harrison, S.C. Crystal Structure of a TOG Domain: Conserved Features of XMAP215/Dis1-Family TOG Domains and Implications for Tubulin Binding. Structure 15: 355-362 (2007).

  • Larsen, N.A., Al-Bassam, J., Wei, R.R., Harrison, S.C. Structural analysis of Bub3 interactions in the mitotic spindle checkpoint. PNAS 104(4): 1201-1206 (2007).

  • Wei, Ronnie R., Al-Bassam, J., Harrison, S.C. The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment. Nature Structural & Molecular Biology 14 (1): 54-59 (2007).

2006

  • Fotin, A., Kirchhausen, T., Grigorieff, N., Harrison, S.C., Walz, T., Cheng, Y. Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy. J. Struct. Biol. 156(3): 453-460 (2006).

  • Zhang, L., Chandran, K., Nibert, M.L., Harrison, S.C. Reovirus µ1 Structural Rearrangements That Mediate Membrane Penetration. Journal of Virology 80 (24): 12367-12376 (2006).

  • Rits-Volloch, S., Frey, G., Harrison, S.C., Chen, B. Restraining the conformation of HIV-1 gp120 by removing a flexible loop. EMBO Journal 25 (20): 5026-5035 (2006).

  • Frey, G., Rits-Volloch, S., Zhang, X.Q., Schooley, R.T., Chen, B., Harrison, S.C. Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion. PNAS 103(38): 13938-13943 (2006).

  • Heldwein, E.E., Lou, H., Bender, F.C., Cohen, G.H., Eisenberg, R.J., Harrison, S.C. Crystal Structure of Glycoprotein B from Herpes Simplex Virus 1. Science 313: 217-220 (2006).

  • Li, F., Berardi, M., Li, W., Farzan, M., Dormitzer, P.D., Harrison, S.C. Conformational States of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein Ectodomain. Journal of Virology 80 (14): 6794-6800 (2006).

  • Wei, R.R., Schnell, J.R., Larsen, N.A., Sorger, P.K., Chou, J.J., Harrison, S.C. Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain. Structure 14: 1003-1009 (2006).

  • Al-Bassam, J., van Breugel, M., Harrison, S.C., Hyman, A. Stu2p binds tubulin and undergoes an open-to-closed conformational change. J. Cell Biol. 172: 1009-1022 (2006).

2005

  • Zhang, X., Ji, Y., Zhang, L., Harrison S.C., Marinescu, D.C., Nibert, M.L., Baker, T.S. Features of reovirus outer capsid protein µ1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0Å. Structure 13: 1545-1557 (2005).

  • Li, F., Li, W., Farzan, M., Harrison, S.C. Sructure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor. Science 309: 1864-1868 (2005).

  • Gonen, T., Cheng, Y., Sliz, P., Hiroaki, Y., Fujiyoshi, Y., Harrison, S.C., and Walz, T. Lipid-protein interactions in double-layered two-dimensional AQPO crystals. Nature 438: 633-638 (2005).

  • Wei, Ronnie R., Sorger, Peter K., and Harrison, Stephen C. Molecular organization of the Ndc80 complex, an essential kinetochore component. PNAS 15: 5363-5367 (2005).

  • Harrison, Stephen C. Mechanism of Membrane Fusion by Viral Envelope Proteins. Advances in Virus Research 64: 231-261 (2005).

  • Chen, B., Vogan E.M., Gong, H., Skehel, J.J., Wiley, D.C., Harrison, S.C. Determining the Structure of an Unliganded and Fully Glycosylated SIV gp120 Envelope Glycoprotein . Structure 13: 197-211 (2005).

  • Chen, B., Vogan E.M., Gong, H., Skehel, J.J., Wiley, D.C., Harrison, S.C. Structure of an unliganded simian immunodeficiency virus gp120 core . Nature 433: 834-841 (2005).

  • Miranda, JJ. L., De Wulf, P., Sorger, P.K., Harrison, S.C. The yeast DASH complex forms closed rings on microtubules. Nature Structural and Molecular Biology 1-6 (2005).

  • Modis, Y., Ogata S., Clements, D. and Harrison, S.C. Variable Surface Epitopes in the Crystal Structure of Dengue Virus. Journal of Virology 79: 1223-1231 (2005).

2004

  • Kim, J., Tao, Y., Reinisch, K.M., Harrison, S.C., Nibert, M.L. Orthoreovirus and Aquareovirus core proteins: conserved enzymatic surfaces, but not protein-protein interfaces. Virus Research 101(39): 15-28 (2004).

  • Heldwein, E.E.,, Macia, E., Wang, J., Yin, H.L., Kirchhausen, T., Harrison, S.C. Crystal structure of the clathrin adaptor protein 1 core. PNAS 101(39): 14108-14113 (2004).

  • Panne, D., Maniatis, T., and Harrison, S.C. Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-β enhancer. EMBO Journal 23: 4384-4393 (2004).

  • Fotin, A., Cheng, Y., Grigorieff, N., Walz, T., Harrison,S.C., Kirchhausen, T. Structure of an auxilin-bound clathrin coat and its implications for the mechanism of sorting. Nature 432: 649-653 (2004).

  • Fotin, A., Cheng, Y., Sliz,P., Grigorieff, N., Harrison, S.C., Kirchhausen, Walz, T. Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature 432: 573-579 (2004).

  • Arnett, K.L., Harrison, S. C. and Wiley D.C. Crystal structure of a human CD3-ε/δ dimer in complex with a UCHT1 single-chain antibody fragment. PNAS 46: 16268-16273 (2004).

  • Larsen, N. and Harrison, S.C. Crystal Structure of the Spindle Assembly Checkpoint Protein Bub3. J. Mol. Biol. 344: 885-892 (2004).

  • Dormitzer, P., Nason, E.B., Prasad, B.V.V., Harrison, S.C. Structural rearrangements in the membrane penetration protein of a non-enveloped virus. Nature 430: 1053-1058 (2004).

  • D. B. Lacy, D. J. Wigelsworth, R. A. Melnyk, S. C. Harrison, and R. John Collier Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation. Proc Natl Acad Sci USA 101: 13147-51 (2004).

  • Chen, B., Cheng, Y., Calder, L., Harrison, S.C., Reinherz, E.L., Skehel, J.J., Wiley, D.C. A Chimeric Protein of Simian Immunodeficiency Virus Envelope glycoprotein gp140 and Escherichia coli Aspartate Transcarbamoylase. Journal of Virology 78: 4508-4516 (2004).

  • Cheng, Y., Zak, O., Aisen, P., Harrison, S.C., Walz, T. Structure of the human transferring receptor-transferrin complex. Cell 116: 565-576 (2004).

  • Modis, Y., Ogata, S., Clements, D. & Harrison, S.C. Structure of the dengue virus envelope glycoprotein after membrane fusion. Nature 427: 313-319 (2004).

  • Van den Berg, B., Clemons, W.M., Jr., Collinson, I., Modis, Y., Hartmann, E., Harrison, S.C., Rapoport, T.A. X-ray structure of a protein-conducting channel. Nature 427: 36-44 (2004).

  • Harrison, S.C. Whither structural biology?. Nature Structural and Molecular Biology 11: 12-15 (2004).

2003

  • Allison, S.L., Tao, Y.J., O’Riordan, G., Mandl, C.W., Harrison, S.C., Heinz, F.X. “Two distinct size classes of immature and mature subviral particles from tick-borne encephalitis virus.” J. Virol. 77: 11357-11366 (2003).
     
  • Modis, Y., Ogata, S., Clements, D., and Harrison, S.C. " A ligand-binding poicket in the dengue virus envelope glycoprotein" PNAS Early edition, 4/29/03.
     
  • Jin, L., Sliz, P., Chen, L., Macian, F., Rao, A., Hogan, P., and Harrison, S.C. "An asymmetric NFAT1 dimer on a pseudo-palindromic kB-like DNA site" Nature Strutural Biology 10: 807-811 (2003).
     
  • Espelin, C., Simons, K., Harrison, S.C., and Sorger, P. "Binding of the Essential Saccharomyces cerevisiae Kinetochore Protein Ndc10p to CDEII". Molecular Biology of the Cell 114: 4557-4568 (2003).
     
  • Odegard, A.L., Chandran, K., Liemann, S., Harrison, S.C., Nibert, M.FL. "A carboxy-proximal disulfide bond between monomers from adjacent _1 trimers in the mammalian reovirus outer capsid: a late and reversible step in virion morphogenesis. In press, J Virol 77 (2003).
     
  • Harrison, S.C. "Variation on an Src-like Theme". Cell 112: 737-740 (2003).
     
  • Sliz, P., Harrison, S.C., and Rosenbaum, G. "Damage in Protein Crystals Depend on X-Ray Dose?" Structure 11: 13-19 (2003).
     

2002

  • Harrison, S.C. "Don C. Wiley (1944-2001)". Molecular Cell 9: 225-227 (2002).
     
  • Tao, Y., Farsetta, D., Nibert, M., Harrison, S.C.,"RNA Synthesis in a Cage-Structural Studies of Reovirus Polymerase^3." Cell 111: 733-745 (2002).
     
  • Liemann, S, Chandran, K., Baker, T.S., Nibert, M., Harrison, S.C. "Structure of the reovirus membrane-penetration protein, _1, in a complex with its protector protein, _3." Cell 108: 283-295 (2002).
     
  • Dormitzer, P.R., Z.-Y. J. Sun, G. Wagner, and S.C. Harrison ."The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site." EMBO J 21:885-897 (2002).
     
  • Dormitzer, P.R., Zhen-Yu J. Sun, Ola Blixt, James C. Paulson, Gerhard Wagner, and Stephen C. Harrison. "Specificity and Affinity of Sialic Acid Binding by the Rhesus Rotavirus VP8* Core." Virology 76, 10512-10517 (2002).
     
  • Jin, L. and Harrison, S.C. "Structure of human calcineurin complexed with cyclosporin A and human cyclophilin" PNAS 99: 13522-13526 (2002).
     
  • Modis, Y., Trus, B., and Harrison S.C. "Atomic model of the papillomavirus capsid" EMBO J. 21: 4754-4762 (2002).
     

2001

  • Chen, X.S., Casini, G., Harrison, S.C., Garcea, R.L. "Papillomavirus Capsid Protein Expression in Escherichia coli: Purification and Assembly of HPV11 and HPV16 L1" J. Mol Biol. 307:173-82 (2001).
     
  • Ferlenghi, I., Clarke, M., Ruttan, T., Allison, S., Schalich, J., Heinz, F., Harrison, S.C., Rey, F., and Fuller, S. "Molecular Organization of a Recombinant Subviral Particle from Tick-Borne Encephalitis Virus", Molecular Cell 7: 593-602, (2001).
     
  • Lin, C.H., Hare, B.J., Wagner, G., Harrison, S.C., Maniatis, T., Fraenkel, E. "A Small domain of CBP/p300 Binds Diverse Proteins: Solution Structure and Functional Studies" Molecular Cell 8: 581-590 (2001).
     
  • Harrison, S.C. "Principles of Virus Structure" in Fields Virology, Fourth Edition, 53-85. (D.M. Knipe, P.M. Howley, et al. Lippincott Williams & Wilkins Publishers, Philadelphia, 2001).
     
  • Olland, A.M., Jan�-Valbuena, J., Schiff, L.A., Nibert, M.L., Harrison, S.C. "Structure of the Reovirus Outer Capsid and dsRNA Binding Protein _3at 1.8 Å Resolution" EMBO J. 20: 979-989, (2001).
     
  • Dormitzer, P.R., H.B. Greenberg, and S.C. Harrison . 2001. Proteolysis of monomeric recombinant rotavirus VP4 yields an oligomeric VP5* core. J. Virol. 75, 7339-7350.
     

2000

  • ter Haar, E., Harrison, S.C., Kirchhausen. T. "Peptide-in-groove interactions link target proteins to the β-propellar of clathrin" PNAS 97: 1096-1100 (2000).
     
  • Lei, M., Lu, W., Meng, W., Parrini, M-C., Eck, M.J., Mayer, B.J., Harrison, S.C. "Structure of PAK1 in an Autoinhibited Conformation Reveals a Multistage Activation Switch." Cell 102: 387-397 (2000).
     
  • Luongo, C.L., Reinisch, K.M., Harrison, S.C., Nibert, M.L. "Identification of the Guanylyltransferase Region and Active Site in Reovirus mRNA Capping Protein _2. J. Biol. Chem. 275: 2804-2810 (2000).
     
  • Chen, X.S., Garcea, R., Goldberg, I., Harrison, S.C. "Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16." Molecular Cell 5: 557-567 (2000).
     
  • Reinisch, K.M., Nibert, M., Harrison, S.C. "The Reovirus Core: Structure of a complex molecular machine." Nature 404: 960-967 (2000).
     
  • Chen, L., Rao., A., Harrison, S.C. "Signal Integration by Transcription-factor Assemblies: Interactions of NF-AT1 and AP-1 on the IL-2 Promoter" Cold Spring Harbor Symposium on Quant. Biol, Vol. LXIV: 527-531. (2000).
     
  • Huang, H. Harrison, S.C. and Verdine, G.L. "Trapping of a catalytic HIV reverse transcriptase-template:primer complex through a disulfide bond." Chemistry & Biology 7: 355-364 (2000).
     
  • Dormitzer, P.R., Greenberg, H.B., Harrison, S.C. "Purified Recombinant Rotavirus VP7 Forms Soluble Calcium-Dependent Trimers" Virology 277: 420-428 (2000).
     
  • Zhou, G., Ferrer, M., Chopra, R., Kapoor, T.M., Strassmaier, T., Weissenhorn, W., Skehel, J.J., Oprian, D., Schreiber S.L., Harrison, S.C., Wiley, D.C. "The Structure of an HIV-1 Specific Cell Entry Inhibitor in Complex with the HIV-1 gp41 Trimeric Core" Bioorganic & Medicinal Chemistry, 8 : 2219-2227 (2000).
     
  • Chen, B., Zhou, G, Kim, M, Chishti, Y, Hussey, R.E., Ely, B, Skehel, J.J., Reinherz, E.L., Harrison, S.C., Wiley, D.C. Expression, purification, and characterization of gp160, the soluble, trimeric, ectodomain of the SIV envelope glycoprotein, gp-160. J. Biol. Chem. 275: 34946-34953 (2000).
     

1999

  • Weissenhorn, W., Dessen, A., Calder, L. J., Harrison, S. C., Skehel, J. J. and Wiley, D. C. "Structural basis for membrane fusion by enveloped viruses." Molecular Membrane Biology 16 (1) 3-9, 1999.
     
  • Xu, W., Doshi, A., Lei, M., Eck, M.J., Harrison, S.C. "Crystal structures of c-Src reveal new features of its auto-inhibitory mechanism." Molecular Cell, 3, 629-638, (1999).
     
  • Ferrer, M. and Harrison, S.C. "Peptide Ligands to Human Immunodeficiency Virus Type-1 gp120 Identified from Phage Display Libraries" J. Virol. 73: 5795-5802 (1999).
     
  • Lawrence, C.M., Ray, S., Babyonyshev,M., Gallusser, R. Harrison, S.C. "Structure of the Ectodomain of Human Transferrin Receptor" Science, 286: 779-782 (1999).
     
  • Ferrer, M., Kapoor, T., Strassmaier, T., Weissenhorn, W., Skehel, J.J., Oprian, D., Schreiber, S., Wiley, D.C., Harrison, S.C. "Selection of gp41-Mediated HIV-1 Cell Entry Inhibitors From Biased Combinatorial Libraries of Non-Natural Binding Elements" Nature Structural Biology 6: 953- 960 (1999).
     
  • Musacchio, A., Smith, C.J., Roseman, A.M., Harrison, S.C., Kirchhausen, T., Pearse, B.M.F. "Functional Organization of Clathrin Coats: Combining Cryo-Electron Microscopy and X-ray Crystallography. Molecular Cell 3: 761-770 (1999).
     
  • Bauer, P.H., Cui, C., Stehle, T., Harrison, S.C., DeCaprio, J.A., Benjamin, T.L. "Discrimination between Sialic Acid-Containing Receptors and Pseudoreceptors Regulates Polyomavirus Spread in the Mouse" J. Virol 73: 5826-5832 (1999).
     

1998

  • Berger, J.M., Fass, D., Wang, J.C., Harrison, S.C. Structural similarities between topoisomerases that cleave on or both DNA strands." PNAS 95: 7876-7881 (1998).
     
  • Chen, L., Glover, J.N.M. Patrick G. Hogan, P.G., Rao, A., Harrison, S.C. "Structure of the DNA Binding Domains from NFAT, Fos and Jun Bound Specifically to DNA" Nature , 392, 42-48 (1998).
     
  • Chen, X., Stehle, T. and Harrison, S.C. "Crystal structure of a C-terminal fragment of polyomavirus internal protein VP2 and its interaction with VP1" EMBO J. 17: 3233-3240 (1998). 3
     
  • Nolte, R.T., Conlin, R.M., Harrison, S.C., Brown, R.S. "Differing roles for zinc fingers in DNA recognition: Structure of a six-finger TFIIIA complex" PNAS 95, 2938-2931 (1998).
     
  • Huse, M., Eck, M.J., Harrison, S.C. "A Zn2+ ion links the cytoplasmic tail of CD4 and the N-terminal region of p56lck." J. Biol. Chem. 273, 18729-18733 (1998).
     
  • TerHaar, E., Musacchio, A., Harrison, S.C., Kirchhausen, T. "Atomic Structure of Clathrin: A _-Propeller Terminal Domain Joins an _-Zig-Zag Linker" Cell 95, 563-573 (1998)
     
  • Huang, H., Chopra, R., Verdine, G.L. and Harrison, S.C. "Structure of a Covalently-Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Nucleoside Analog Drug Resistance." Science, 282, 1669-1675 (1998).
     
  • Jacobs, M.D. and Harrison, S.C. "Structure of an NF_B/I_B_ Complex" Cell 95, 749-758 (1998).
     

1997

  • Xu, W., Harrison, S.C. & Eck, M.J. "Three-dimensional structure of the tyrosine kinase c-Src" Nature 385, 595-602 (1997).
     
  • Casasnovas, J.M., Springer, T.A.,Liu, J.H., Harrison, S.C. & Wang, J.H. "The Crystal Structure of ICAM-2 Reveals a Distinctive Integrin Recognition Surface" Nature 387, 312-315 (1997).
     
  • Stehle, T. & Harrison, S.C. "High-resolution structure of a polyomavirus VP1-oligosaccharide complex: implications for assembly and receptor binding" EMBO J. 16, 5139-5148, 1997.
     
  • Weissenhorn, W., Dessen, A., Harrison, S.C., Skehel, J.J., Wiley, D.C. "Atomic Structure of an Ectodomain from HIV-1 gp 41" Nature 387, 426 - 430, 1997.
     
  • Ferrer, M., Godbout, K.L., Sullivan, B.J., Austen, D.A., Sanderson, C.T., Kelley, K.C., Osburne, M.S., Harrison, S.C., van Schravendijk, M "Construction and characterization of a radio-iodinatable mutant of recombinant human CD4" J. Immunol. Methods 210, 215-225 (1997).
     

1996

  • Harrison, S.C. "Peptide-Surface Association: The Case of PDZ and PTB Domains" Cell 86, 341-343 (1996).
     
  • Musacchio, A., Cantley, L.C. & Harrison, S. C. "Crystal Structure of the breakpoint cluster region-homology domain from phosphoinositide 3-kinase p85 a subunit ." PNAS 93, 14373-78 (1996).
     
  • Harrison, S.C., Skehel, J.J. & Wiley, D.C. "Virus Structure" in Fields Virology, Third Edition, 59-99. (B.N. Fields, D.M. Knipe, P.M.Howley, et al. Lippincott-Raven Publishers, Philadelphia, 1996).
     
  • M�ller, C.W., Rey, F.A. & Harrison "Comparison of two different DNA-binding modes of the NF-kB p50 homodimer." Nature Structural Biology 3, 224-227 (1996).
     
  • Berger, J., Gamblin, S.J., Harrison, S.C., & Wang, J.C. "Structure at 2.7 Å resolution of a 92K yeast DNA topoisomerase II fragment." Nature, 379, 225-232. (1996).
     
  • Yan, Y., Stehle, T., Liddington, R.C., Zhao, H. & Harrison, S.C. "Structure Determination of Simian Virus 40 and Murine Polyomavirus By a Combination of 30-fold and 5-fold Electron-density Avaraging." Structure 4, 157-164 (1996).
     
  • Stehle, T., Gamblin, S.J., Yan, Y. & Harrison, S.C. "The Structure of Simian Virus 40 Refined at 3.1 Å Resolution." Structure 4, 165-182 (1996).
     
  • Stehle, T., & Harrison, S.C. "Crystal Structures of Murine Polyomavirus in Complex with Straight-chain and Branched-chain Sialyloligosaccharide Receptor Fragments." Structure 4, 183-194 (1996).
     
  • Roca, J., Berger, J.M., Harrison, S.C. & Wang, J.C. "DNA Transport by Type II DNA Topoisomerase: Direct Evidence for a Two-Gate Mechanism." PNAS, 93, 4057-4062. 1996.
     
  • Eck, M.J., Pluskey, S., Tr�b, T., Harrison, S.C., & Shoelson, S.E. "Spatial Constraints on the Recognition of Phosphoproteins by the tandem SH2 Domains of the Phosphatase SH-PTP2" Nature 379, 277-280 (1996).
     
  • Nolte, R.T., Eck, M.J., Schlessinger, J., Shoelson, S.E. & Harrison, S.C. "Crystal Structure of the PI 3 -Kinase P85 Amino-Terminal SH2 Domain and its Phosphopeptide Complexes" Nature Structural Biology, 3, pp. 364-374 (1996).
     
  • Weissenhorn, W., Eck, M.J., Harrison, S.C., & Wiley, D.C. "Phosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitro" Euro. J. Biochem. 238: 440-445 (1996).
     
  • Fass, D., Harrison, S.C. & Kim, P.S. "Retrovirus envelope domain at 1.7 Å resolution" Nature Structural Biology 3, 465-469 (1996).
     

1995

  • Glover, J.N.M., & Harrison, S.C. "The Crystal Structure of the Heterodimeric bZIP Transcription Factor c-Fos:c-Jun Bound to DNA." Nature, 373, 257-261. 1995
     
  • Rodgers, D.W., Gamblin, S.G. Harris, B.A., Ray, S., Culp, J.S., Hellmig, B., Woolf, D.J., Debouck, C. & Harrison, S.C. "The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1." PNAS, 92, 1222-1226 (1995).
     
  • Mller, C.W., Rey, F.A., Sodeoka,M., Verdine, G.L., & Harrison, S.C. "Structure of the NF-kB p50 homodimer bound to DNA. Nature, 373, 311-317 1995.
     
  • Harrison, S.C. "Virus structures and conformational rearrangements" Current Opinion in Structural Biology 5, 157-164 (1995).
     
  • Rey, F.A., Heinz, F. X., Mandl, C., Kunz, C. & Harrison, Stephen C. "The envelope glycoprotein from tick-borne encephalitis virus at 2 Å resolution." Nature, 375, 291-298(1995).
     
  • Mller, C.W. & Harrison, S.C. "The structure of the NF-kB p50:DNA complex: A starting point for analyzing the Rel family." FEBS, 369, 113-117(1995).
     
  • Bauer, P.H., Bronson, R.T., Fung, S.C., Freund, R., Stehle, T., Harrison, S.C. & Benjamin, T.L. "Genetic and Structural Analysis of a Virulence Determinant in Polyoma VP1" J. Virol.69, 7925-7931 (1995).
     
  • Glover, J.N.M., Chen, L., Verdine, G.L., & Harrison, S.C. "A Structural Analysis of the bZIP Family of Transcriptin Factors: Dimerization, DNA Binding and Interactions with Other Transcription Factors" in Biol. Struct. and Dynamics. Proceedings of the Ninth Conversation, SUNY Albany, NY 1995 (Eds. Ramaswany H. Sarma and Mukti H. Sarma, Adenine Press 1996).
     

1994

  • Barouch, D.H. & Harrison, S.C. "The Interaction Between the Major and Minor Coat Proteins of Polyomavirus" J. Virol., 68, 3982-3989 (1994).
     
  • Harrison, S.C. "CD4 - the receptor for HIV." in Cellular Receptors for Animal Viruses (editor, E. Wimmer), Chapter 3. (Cold Spring Harbor Laboratory Press, New York, 1994).
     
  • Eck, M.J., Atwell, S.K., Shoelson, S.E. & Harrison, S.C. "Structure of the regulatory domains of the Src-family tyrosine kinase p56lck." Nature, 368, 764-769 (1994).
     
  • Ellenberger, T., Fass, D., Arnaud, M. & Harrison, S.C. "Crystal Structure of Transcription Factor E47: E-box Recognition by a Basic Region Helix-loop-helix Dimer" Genes & Development, 8, 970-980(1994).
     
  • Stehle, T., Yan, Y., Benjamin, T.L. & Harrison, S.C. "Structure of murine polyomavirus complexed with an oligosaccharide receptor fragment." Nature, 369, 160-163 (1994).
     
  • Marmorstein, R. & Harrison, S.C. "Crystal Structure of a PPR1-DNA Complex: DNA Recognition by Proteins Containing a Zn2Cys6 Binuclear Cluster." Genes & Development, 8, 2504-2512. (1994)
     
  • Rodgers, D.W. "Cryocrystallography." Structure, 2, 1135-1140 (1994).
     

1993

  • Shimon, L.J.W. & Harrison, S.C. "The Phage 434 OR2/R1-69 Complex at 2.5 Å Resolution" J. Mol. Biol., 232, 826-838 (1993).
     
  • Garrett, T.P.J., Wang, J., Yan, Y., Liu, J., Harrison, S.C. "Refinement and analysis of the structure of the first two domains of human CD4" J.Mol. Biol 234, 763-778 (1993).
     
  • Eck, M.J. Shoelson, S.E., Harrison, S.C. "Recognition of a high affinity phosphotyrosyl peptide by the Src homology domain of p56lck" Nature, 362, 87-91 (1993).
     
  • Liddington R.C. and Harrison, S.C. "Structure of simian virus 40." Structure 0, xxii-xxiii (1993).
     
  • Moebius, U., Pallai, P., Harrison, S.C. Reinherz, E.L. "Delineation of an extended surface contact area on human CD4 involved in class II MHC binding" PNAS, 90, 8259-8263 (1993).
     
  • Harrison, S.C. "Structure and Interactions of an Ig-superfamily Adhesion Molecule" Accounts in Chemical Research, 26, 449-453(1993).
     
  • Yan, Y., Winograd, E., Viel. A., Cronin, T., Harrison, S.C. and Branton, D. "Atomic Structure of the Repetitive Segments of Spectrin" Science, 262, 2027-2030 (1993).
     
  • Rodgers, D.W. & Harrison, S.C. "The complex between phage 434 repressor DNA binding domain and operator site OR3: structural differences between consensus and non-consensus half-sites." Structure, 1, 227-240 (1993).
     

1992

  • Baleja, J.D., Marmorstein, R., Harrison, S.C., Wagner, G. "Solution Structure of the DNA-binding Domain of Cd2-GAL4 from Saccharomyces cerevisiae" Nature (1992)356, 450-453.
     
  • Marmorstein, R., Carey,M., Ptashne, M., Harrison, S.C. "DNA Recognition by GAL4: structure of a protein/DNA complex" Nature 356: 408-414 (1992).
     
  • Harrison, S.C., Strong, R.K., Schlesinger, S., Schlesinger, M.J. "Crystallization of Sindbis Virus and its Nucleocapsid"J.Mol. Biol 226: 277-280 (1992).
     
  • Harrison, S.C. "Viruses" Current Opinion in Structural Biology 2: 293-299. (1992)
     
  • Moebius, U., Clayton, L., Abraham, S., Harrison S.C., Reinherz, E.L. "The HIV gp120 binding site on CD4: Delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high resolution CD4 atomic structure " J. Exp. Med. 176, 507-517 (1992).
     
  • Moebius, U., Clayton, L.K., Abraham, S., Diener, A., Yunis, J.J., Harrison, S.C. & Reinherz, E.L. "The HIV-gp120 Binding C'C" Ridge of CD4 Domain 1 is Also Involved in Interaction with Class II MHC Molecules" PNAS 89, 12008-12012. (1992).
     
  • Harrison, S.C. "Molecular characteristics of the regulatory switch in phages 434 and lambda" in Transcriptional Regulation (ed. by K. Yamamoto & S. McKnight) Ch. 17, 449-473 (Cold Spring Harbor Laboratory Press, New York 1992).
     
  • Harrison, S.C., Wang, J., Yan, Y., Garrett, T., Liu, J., Moebius, U., Reinherz, E.L. "Structure and Interactions of CD4" Cold Spring Harbor Laboratory Symposia on Quantitative Biology 57, 541-548 (1992).
     
  • Harrison, S.C., Wang, J., Yan, Y., Garrett, T., Liu, J., Moebius, U., Reinherz, E.L. "Structure and Interactions of CD4" Proceedings of Novo Nordisk Foundation Symposium No. 6 'Leukocyte Adhesion' Basic and Clinical Aspects (Elsevier Publishers, Holland, C.G. Gahmberg, T. Mandrup-Poulsen, L. Wogensen Bach, B. Hlt, eds.1992) pp. 255-269.
     
  • Ellenberger, T.E., Brandl, C.J., Struhl, K., Harrison, S.C. "The GCN4 Basic Region Leucine Zipper Binds DNA as a Dimer of Uninterrupted a-helices: Crystal Structure of the Protein-DNA Complex" Cell 71, 1223-1237 (1992).
     

1991

  • Harrison, S.C. "Viruses" in Current Opinion in Structural Biology Vol. 1/2 1, 288-295 (1991).
     
  • Harrison, S.C. "A structural taxonomy of DNA-binding domains" Nature (1991) 353, 715-719.
     
  • Liddington, R.C., Yan, Y, Moulai, J., Sahli, R., Benjamin, T.L., Harrison, S.C. "Structure of Simian Virus 40 at 3.8-Å resolution" Nature 354, 278-284 (1991).
     
  • Mondragon, A. and Harrison, S.C. "The Phage 434 Cro/OR1 Complex at 2.5 Å Resolution" J. Mol. Biol. 219, 321-334 (1991).
     
  • Borhani, D. and Harrison, S.C. "Crystallization and X-ray Diffraction Studies of a Soluble Form of Human Transferrin Receptor" J. Mol. Biol. 218, 685-689 (1991).
     
  • Harrison, S.C. "What Do Viruses Look Like?" The Harvey Lectures, Series 85, 127-152. Wiley-Liss, Inc (1991).
     

1990

  • S.C. Harrison . "Principles of Virus Structure" in Fundamental Virology, 2nd Ed. pp. 37-61. (Raven Press, NY; Fields and Knipe, ed. 1990).
     
  • C.O. Pabo, A.K.Aggarwal, S.R. Jordan, L.J. Beamer, U.R. Obeysekare, S.C. Harrison "Conserved Residues Make Similar Contacts in Two Repressor-Operator Complexes." Science 247: 1210-1213 (1990).
     
  • S.C. Harrison and A.K. Aggarwal. "DNA Recognition by Proteins with the helix-turn-helix motif." in Annual Rev. of Biochem.,59: 933-69 (1990).
     
  • N. Wei, L. A. Heaton, T.J. Morris and S.C. Harrison "Structure and Assembly of Turnip Crinkle Virus V. Identification of Coat Protein Binding Sites on RNA" J. Mol. Biol. 214, 85-95 (1990).
     
  • R.K. Strong and S.C. Harrison ."Proteolytic Dissection of Sindbis Virus Core Protein" J. Virology 64, 3992-3994 (1990).
     
  • J.W. Campbell, I.J. Clifton, T.J. Greenhough, J. Hajdu, S.C. Harrison , R.C. Liddington, A.K. Shrive. "Calcium Binding Sites in Tomato Bushy Stunt Virus Visualized by Laura Crystallography" J. Mol. Biol. 214, 627-632.(1990).
     
  • Coombs, K.M., Fields, B.N. and Harrison, S.C. "Crystallization of the reovirus type 3 Dearing core: Crystal packing is determined by the l protein." J. Mol. Biol. 215, 1-5 (1990).
     
  • Weiss, M.A., Ellenberger, T., Wobbe, C.R., Lee, J.P., Harrison, S.C., Struhl, K. Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA" Nature 347, 575-578 (1990).
     
  • Harrison, S.C. "Common features in the structures of some icosahedral viruses: a partly historical overview" in Seminars in Virology,1, W.B. Saunders Company pp 387-403 (1990).
     
  • Wang, J., Garrett, T., Yan, Y., Liu, J., Rodgers, D., Garlick, R.L., Tarr, G.E., Husain, Y., Reinherz, E.L., Harrison, S.C. "Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains" Nature 348, 411-418 (1990).
     
  • Heinz, F.X., Mandl, C.W., Holzmann, H., Kunz, C., Harris, B.A., Rey, F., Harrison, S.C. "The Flavivirus Envelope Protein E: Isolation of a Soluble Dimeric Form from Tick-Borne Encephalitis Virus and Its Crystallization" J. Virol. 65, 5579-5583 (1990).

     

1989

  • A. Mondragon, C. Wolberger and S.C. Harrison . "Structure of Phage 434 Cro Protein at 2.35 Å Resolution." J. Mol. Biol., 205, 179-188 (1989).
     
  • S.C. Harrison . "Finding the Receptors." Nature 338, 205-206 (1989).
     
  • A. Mondragon, S. Subbiah, S.C. Almo, M. Drottar and S.C. Harrison "Structure of the Amino Terminal Domain of Phage 434 Repressor at 2.0 Å Resolution." J. Mol. Biol., 205 189-200 (1989).
     
  • A.P. Turkewitz and S.C. Harrison "Concentration of Transferrin Receptor in Human PlacentalCoated Vesicles." J. Cell. Biol., 108: 2127-2135 (1989).
     
  • S. Subbiah and S.C. Harrison ."A simulated annealing approach to the search problem of protein crystallography." Acta Cryst. A45, 337-342 (1989).
     
  • S. Subbiah and S.C. Harrison ."A Method for Multiple Sequence Alignment with Gaps" J. Mol. Biol. 206, 539-548 (1989).
     
  • S.C. Harrison . "Common Features in the Design of Small RNA Viruses." in Concepts in Viral Pathogenesis III pp. 3-19 (Springer-Verlag New York, Inc.,1989).
     

1988

  • S.C. Harrison , J.E. Anderson, G.B. Koudelka, A. Mondragon, S. Subbiah, R.P. Wharton, C.Wolberger and M. Ptashne. "Recognition of DNA Sequences by the Repressor of Bacteriophage 434". Biophysical Chemistry 29, 31-37 (1988).
     
  • S.C. Harrison , J.E. Anderson, Y-C. Dong, M. Drottar, G.B. Koudelka, A. Mondragon, S. Subbiah,R.P. Wharton, C. Wolberger and M. Ptashne. "Recognition of DNA Sequences by the Repressor and Cro Proteins of Bacteriophage 434." Proceedings of the Symposium Louis Pasteur, 1987. Bulletin Institute Pasteur 86, 55-64 (1988).
     
  • A.P. Turkewitz, J.F. Amatruda, D. Borhani, S.C. Harrison , and A.L. Schwartz. "A High Yield Purification of the Human Transferrin Receptor and Properties of Its Major Extracellular Fragment." J. Biol. Chem. 263, No. 17, pp. 8318-8325. (1988).
     
  • G.B. Koudelka, P. Harbury, S.C. Harrison , M. Ptashne. "DNA Twisting and the Affinity of Bacteriophage 434 Operator for Bacteriophage 434 Repressor." PNAS.USA 85: 4633-4637 (1988).
     
  • C. Wolberger, Y. Dong, M. Ptashne and S.C. Harrison . "Structure of a Phage 434 Cro/DNA Complex." Nature 335, 789-795 (1988).
     
  • A. Aggarwal, D. Rodgers, M. Drottar, M. Ptashne, and S.C. Harrison . "Recognition of a DNA Operator by the Repressor of Phage 434: a View at High Resolution." Science 242, 899-907 (1988).
     
  • A.P. Turkewitz, A.L. Schwartz and S.C. Harrison . "A pH-Dependent Reversible Conformational Transition of the Human Transferrin Receptor Leads to Self-Association." J. Biol. Chem., 263, 16309-16315 (1988).
     

1987

  • J. Carrington, T. J. Morris, P. G. Stockley, and S.C. Harrison "Structure and Assembly of Turnip Crinkle Virus, IV: Analysis of the Coat Protein Gene and Implications of the Subunit Primary Structure." J. Mol. Biol. 194, 265-276 (1987).
     
  • S.C. Harrison, P. K. Sorger, P.G. Stockley, J. Hogle, R. Altman, and R.K. Strong. "Mechanism of RNA VirusAssembly and Disassembly." in Positive Strand RNA Viruses,. Alan R. Liss, Inc., 379-395 (1987).
     
  • J. E. Anderson, M. Ptashne, and S.C. Harrison "Structure of the repressor-operator complex of bacteriophage 434." Nature 326, 846-852 (1987).
     
  • G. B. Koudelka, S.C. Harrison, and M. Ptashne. "Non-contacted Bases Affect the Operator Affinities of 434 Repressor and Cro." Nature 326, 886-888 (1987).
     
  • C. Wolberger and S.C. Harrison "Crystallization and X-ray Diffraction Studies of a 434 Cro-DNA Complex." J. Mol. Biol. 196, 951-954 (1987).
     
  • M. Blum, P. Metcalf, S.C. Harrison, and D. C. Wiley. "A System for Collection and On-line Integration of X-ray Diffraction Data from a Multiwire Area Detector." J. Appl. Cryst.20, 235-242 (1987).
     
  • T. Kirchhausen, P. Scarmato, S.C. Harrison , J.J. Monroe, E.P. Chow, R.J. Mattaliano, K.L. Ramachandran, J.E. Smart and J. Brosius. "Clathrin Light Chains LCA and LCB are Similar, Polymorphic, and Share Repeated Heptad Motifs." Science 236, 320-324(1987).
     

1986

  • R. Durbin, R. Burns, J. Moulai, P. Metcalf, D. Freymann, J. Anderson, S.C. Harrison, and D. C.Wiley. "Protein, DNA, and Virus Crystallography with a Focused Imaging Proportional Counter." Science 232,1127-1132 (1986).
     
  • S.C. Harrison "Alphavirus Structure," Chapter 2 of The Togaviridae and Flaviviridae (S. and M. Schlesinger, eds., Plenum Publishing Corp., 1986).
     
  • J. M. Hogle, A. Maeda, and S.C. Harrison "Structure and Assembly of Turnip Crinkle Virus, I:X-ray Crystallographic Structure Analysis at 3.2 Å Resolution." J. Mol. Biol. 191, 625-638 (1986).
     
  • P. K. Sorger, P. G. Stockley, and S.C. Harrison "Structure and Assembly of Turnip Crinkle Virus, II: Mechanism of Reassembly in Vitro." J. Mol. Biol. 191,. 639-658 (1986).
     
  • P. G. Stockley, A. L. Kirsh, E. P. Chow, J. E. Smart, and S.C. Harrison "Structure of TurnipCrinkle Virus, III: Identification of a Unique Coat Protein Dimer." J. Mol. Biol. 191,721-725 (1986).
     
  • T. Kirchhausen, S.C. Harrison, and J. Heuser. "Configuration of Clathrin Trimers: Evidence from Electron Microscopy." J. of Ultrastructure and Mol. Structure Research 94,199-208 (1986).
     

1985

  • S.C. Harrison "Principles of Virus Structure" in Virology (ed. B. N. Fields et al.; Raven Press, New York), 27-44 (1985).
     
  • S.C. Harrison . "First comparison of two animal viruses in three dimensions." Nature 317, 382-384, News and Views (1985).
     
  • S.C. Harrison . "Protein Structures. Two for the price of one." Nature 313, 736-737, News and Views (1985).
     
  • S.C. Harrison and R. Durbin. "Is There a Single Pathway for the Folding of a Polypeptide Chain?" Proc. Natl. Acad. Sci. USA 82, 4028-4030 (1985).
     
  • T. Kirchhausen, J.C. Wang, and S.C. Harrison . "DNA Gyrase and its Complexes with DNA: Direct Observation by Electron Microscopy." Cell 41, 933-943 (1985).
     
  • S.C. Harrison, F. K. Winkler, C. E. Schutt, and R. M. Durbin. "Oscillation Method with Large Unit Cells," in Methods in Enzymology. Vol. 114, Part A (eds. Colowick and Kaplan, Academic Press, Inc., Orlando, FLA, 1985).
     
  • J. Anderson, M. Ptashne, and S.C. Harrison "A Phage Repressor-Operator Complex at 7 Å Resolution." Nature 316, 596-601 (1985).
     
  • F.D. Bushman, J. Anderson, S.C. Harrison , and M. Ptashne. "Ethylation Interference and X-ray Crystallography Identify Similar Interactions Between 434 Repressor and Operator." Nature 316, 651-653 (1985).
     
  • S.C. Harrison and T. Kirchhausen. "Molecular Interactions in Receptor Cycling and Endocytosis by Clathrin-Coated Vesicles." TIBS Centerfold, October 1985.
     

1984

  • J. Anderson, M. Ptashne, and S.C. Harrison "Cocrystals of the DNA-binding domain of phage 434 repressor and a synthetic phage 434 Operator." Proc. Nat'l. Acad. Sci. USA 81,1307-1311 (1984).
     
  • S.C. Harrison "Structures of Viruses" in The Microbe 1984: Part 1 Viruses (ed. B. W. J. Mahy and J. R. Pattison), Soc. Gen. Microbiol. Symposium 36, pp. 29-73 (1984).
     
  • P. Hopper, S.C. Harrison, and R. Sauer. "Structure of Tomato Bushy Stunt Virus V: Protein Sequence Determination and its Structural Implications." J. Mol. Biol. 177, 701-713 (1984).
     
  • S C. Harrison. "Multiple Modes of Subunit Association in the Structures of Simple Spherical Viruses." TIBS Vol. 9, No. 1, pp. 345-351 (1984).
     
  • T. Kirchhausen, J. Wang, and S.C. Harrison "Structural Studies of DNA Gyrase." Proceedings of the 42nd Annual Meeting of the Electron Microscopy Society of America (1984)
     
  • T. Kirchhausen and S.C. Harrison "Structural Domains of Clathrin Heavy Chains." J. Cell.Biol. 99: 1725-34 (1984).
     

1983

  • T. Kirchhausen, S.C. Harrison, P. Parham, and F. M. Brodsky. "Location and Distribution of the Light Chains in Clathrin Trimers." Proc. Nat. Acad. Sci. USA 80, 2481-85 (1983).
     
  • S. C. Harrison and T. Kirchhausen. "Clathrin, Cages, and Coated Vesicles." Cell 33, 650-652 (1983).
     
  • S.C. Harrison " Virus Structure: High Resolution Perspectives" in Advances in Virus Research.Vol. 28 (eds. M. Lauffer and K. Mamamorosch) Academic Press, Inc., New York, 1983; pp. 175-240 (1983).
     
  • A. J. Olson, G. Bricogne, and S.C. Harrison "Structure of Tomato Bushy Stunt Virus, IV: The Virus Particle at 2.9 Å Resolution." J. Mol. Biol. 171. 61-93 (1983).
     
  • J. Hogle, T. Kirchhausen, and S.C. Harrison "Divalent Cation Sites in Tomato Bushy Stunt Virus: Difference Maps at 2.9 Å Resolution." J. Mol. Biol., 171, 95-100 (1983).
     
  • S.C. Harrison "Packaging of DNA into Bacteriophage Heads - A Model." J. Mol. Biol. 171, 577-580 (1983).

     

1982

  • J. S. Golden and S.C. Harrison "Proteolytic Dissection of Turnip Crinkle Virus Subunit in Solution." Biochem. 16, 3862 (1982).
     
  • I. K. Robinson and S.C. Harrison "Structure of the Expanded State of Tomato Bushy StuntVirus." Nature 297, 563 (1982).
     

1981

  • S.C. Harrison "Molecular Organization of Virus Particles: Implications for Assembly." Prog. Clin. Biol. Res. 64, 3 (1981).
     
  • S.C. Harrison, A.J. Olson, J.S. Golden, J.M. Hogle, R.C. Ladner, I.K. Robinson, R.T Sauer "Recognition and Specificity in Assembly of Icosahedral Viruses: TBSV and TCV." Structural Aspects of Recognition and Assembly in Biological Macromolecules. Balaban ISS, Rehovot and Philadelphia (1981).
     
  • T. Kirchhausen and S.C. Harrison "Protein Organization in Clathrin Trimers." Cell 23, 755 (1981).
     

1980

  • S.C. Harrison "Molecular Packing of Nucleic Acids in Spherical Viruses." in Biological Recognition and Assembly (eds. D. S. Eisenberg, J. A. Lake and C. F. Fox) Alan R. Liss, New York, 1980; p. 301.
     
  • S.C. Harrison . "Virus Crystallography Comes of Age." Nature 286, 558-559, News and Views (1980).
     
  • S.C. Harrison "Protein Interfaces and Intersubunit Bonding: The Case of Tomato Bushy Stunt Virus." Biophys. J. 32,139-153. (1980).
     
  • M. G. Munowitz, C. M. Dobson, R. G. Griffin, and S.C. Harrison "On the Rigidity of RNA in Tomato Bushy Stunt Virus." J. Mol Biol. 141, 327 (1980).
     

1979

  • F. K. Winkler, C. E. Schutt, and S.C. Harrison "The Oscillation Method for Crystals with Very Large Unit Cells." Acta Cryst. A35, 901(1979).
     

1978

  • S.C. Harrison "Structure of Simple Viruses: Specificity and Flexibility in Protein Assemblies." TIBS 3, 3 (1978).
     
  • W. C. Earnshaw, J. King, S.C. Harrison, and F. A. Eiserling. "The Structural Organization of DNA Packaged within the Heads of T4 Wild-Type, Isometric and Giant Bacteriophages." Cell 14, 559 (1978).
     
  • S.C. Harrison, A. J. Olson, C. E. Schutt, F. K. Winkler, and G. Bricogne. "Tomato Bushy Stunt Virus at 2.9 Å Resolution." Nature 276, 368 (1978).
     
  • C. H. von Bonsdorff and S.C. Harrison "Hexagonal Glycoprotein Arrays from Sindbis Virus Membranes" J. Virol. 28, 578 -583. (1978).
     

1977

  • F. K. Winkler, C. E. Schutt, S.C. Harrison, and G. Bricogne. "Tomato Bushy Stunt Virus at 5.5 ÅResolution." Nature 265, 509 (1977).
     
  • McCarthy, M. and Harrison, S.C. "Glycosidase Susceptibility: aProbe for the Distribution of Glycoprotein Oligosaccharides in Sindbis Virus." J. Virol. 23. 61-73. (1977).
     
  • W. C. Earnshaw and S.C. Harrison "DNA arrangement in Isometric Phage Heads." Nature 268, 598 (1977).
     
  • G. Bricogne, S.C. Harrison, F. K. Winkler, and others. Report of CECAM Workshop on Virus Crystallography (1977).
     

1976

  • W. Earnshaw, S. Casjens, and S.C. Harrison "X-ray Diffraction from P22 Heads." J. Mol. Biol.104, 387 (1976).
     
  • S.C. Harrison and R. D. Kornberg. "X-ray Diffraction from Isolated Repeat Units of Chromatin," in Molecular Mechanisms in the Control of Gene Expression (Academic Press, 1976).
     

1975

  • H. von Bonsdorff and S.C. Harrison "Sindbis Virus Glycoproteins Form a RegularIcosahedral Surface Lattice." J. Virol. 16, 141 (1975).
     
  • C. Cohen, S.C. Harrison, and R. E. Stephens. "X-ray Diffraction from Microtubules." J. Mol. Biol. 59, 375 (1975).
     
  • C. Cohen, D. DeRosier, S.C. Harrison, R. E. Stephens, and J. Thomas. "X-ray Patterns from Microtubules." Ann. New York Acad. Sci. 254, 53 (1975).
     
  • A. Jack, S.C. Harrison, and R. A. Crowther. "Structure of Tomato Bushy Stunt Virus, II. Comparison of Results Obtained by Electron Microscopy and X-ray Diffraction." J. Mol. Biol. 97, 163 (1975).
     
  • S.C. Harrison and A. Jack. "Structure of Tomato Bushy Stunt Virus, III. Three-Dimensional X-ray Diffraction Analysis at 16 Å Resolution." J. Mol. Biol. 97, 173 (1975).
     
  • A. Jack and S.C. Harrison "On the Interpretation of Small-Angle X-ray Solution Scattering from Spherical Viruses." J. Mol. Biol. 99,15 (1975).
     
  • D. H. Ohlendorf, M. L. Collins, E. 0. Puronen, L. J. Banaszak, and S.C. Harrison "CrystallineLipoprotein Phosphoprotein Complex in Oocytes from Xenopus laevis: Determinationof Lattice Parameters by X-ray Crystallography and Electron Microscopy." J. Mol.Biol. 99,153 (1975).
     

1974

  • A. Ziegler, S.C. Harrison, and R. Leberman. "Minor Proteins in Tomato Bushy Stunt and Turnip Crinkle Viruses." Virology 59, 509 (1974).
     
  • S.C. Harrison, A. Jack, D. Goodenough, and B. Sefton. "Structural Studies of Spherical Viruses." J. Supramolec. Structure 2, 486 (1974).
     

1973

  • Y. DuPont, S.C. Harrison, and W. Hasselbach. "Molecular Organization in the Sarcoplasmic Reticulum Membrane Studied by X-ray Diffraction." Nature 244, 555 (1973). 
     
  • S.C. Harrison "Biological Diffraction" in Research Application of Synchrotron Radiation. Brookhaven National Laboratory, BNL-50381(1973).
     

1971

  • S.C. Harrison, D. L. D. Caspar, D. Camerini-Otero, and R. M. Franklin. "Lipid and Protein Arrangement in Bacteriophage PM2." Nature New Biol.; 229,197 (1971).
     
  • S.C. Harrison, A. David, J. Jumblatt, and J. E. Darnell. "Lipid and Protein Organization in Sindbis Virus." J. Mol. Biol. 60, 523-528 (1971).
     
  • S.C. Harrison "Structure of Tomato Bushy Stunt Virus at 25 Å Resolution." Cold Spr. Harb.Symp. Quant. Biol. XXXVI, 495 (1971).
     
  • R. M. Franklin, S.C. Harrison, U. Petterson, L. Philipson, C. Braden, and P. E. Werner."Structural Studies on the Adenovirus Hexon." Cold Spr. Harb. Symp. Quant. Biol.XXXVI, 503 (1971).
     

1970

  • K. Weber, J. Rosenbusch, and S.C. Harrison "Structure of Tomato Bushy Stunt Virus." Virology 41, 763 (1970).
     

1969

  • S.C. Harrison "Structure of Tomato Bushy Stunt Virus. I. The Spherically Averaged Electron Density." J. Mol. Biol. 42 457 (1969).
     

1968

  • S.C. Harrison "A Point Focusing Camera for Single-Crystal Diffraction." J. Appl. Cryst. 1, 84 - 90. (1968).
     

1967

  • S.C. Harrison "The Structure of Tomato Bushy Stunt Virus." Ph.D. Thesis, Harvard University, 1967.
     

1966

  • J. M. Diamond and S.C. Harrison "The Effect of Membrane Fixed Charges on Diffusion Potentials and Streaming Potentials." J. Physiol. 183, 37 (1966).
     

1965

  • S.C. Harrisonand E. R. Blout. "Reversible Conformational Changes of Myoglobin and Apomyoglobin." J. Biol. Chem. 240, 299 (1965).